Results 31 to 40 of about 1,360 (246)
Maize Breeding in the Highlands of Ecuador, Peru, and Bolivia: A Review
Maize is one of the most important staple crops in the highlands of the Andean region of Ecuador, Peru, and Bolivia. Most seeds come from landraces, with their own kernel characteristics. The kernels are used for the elaboration of traditional dishes and
José Luis Zambrano +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
This paper presents a case study of Cuba's Local Agricultural Innovation Project (PIAL for its initials in Spanish), with a focus on its gender-specific elements.
Barbara Benítez +10 more
doaj +1 more source
Approaches and Advantages of Increased Crop Genetic Diversity in the Fields
Crop genetic diversity is the most important factor for a long-term sustainable production system. Breeding and production strategies for developing and growing uniform and homogenous varieties have created many problems.
Bal Krishna Joshi +4 more
doaj +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Diversity as a Plant Breeding Objective
This review paper addresses the importance of increasing agrobiodiversity to cope with climate change and, at the same time, providing a sufficient amount of healthy food.
Salvatore Ceccarelli, Stefania Grando
doaj +1 more source
PARTICIPATORY PLANT BREEDING IN WATER-LIMITED ENVIRONMENTS
Drought is one of the major factors limiting crop production worldwide. Dry areas are a much less homogeneous population of target environments than areas with high and reliable rainfall. In this paper we argue that a decentralized participatory plant breeding programme can address the complexity of dry areas, characterized by high and repeatable ...
Ceccarelli, Salvatore +2 more
openaire +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
The interest of farmers in growing lettuce landraces is increasing, as landrace varieties prove particularly appealing to consumers striving to purchase natural, local, and high-quality produce. Although high genetic diversity exists in the landrace gene
Joan Casals Missio +8 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source

