Results 61 to 70 of about 32,859 (307)

Combining PPB and marker-assisted selection: strategies and experiences with rice [PDF]

, 2016
Participatory plant breeding should not preclude the use of modern biotechnological ...
Prasad, S, Steele, K, Virk, D, Witcombe, J   +3 more
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Improved Tomato Breeding Lines Adapted to Organic Farming Systems Have Enhanced Flavor, Yield, and Disease Resistance

HortScience
Most of the tomato (Solanum lycopersicum) varieties currently used in organic farming were bred for conventional farming, often characterized by high-input use.
Ambar Carvallo Lopez, Marissa Nix, Thomas Hickey, Julie C. Dawson   +3 more
doaj   +1 more source

State of the art of existing breeding initiatives & actions planned to strengthen collaborations [PDF]

, 2019
State of the art of existing breeding initiatives3Introduction In order to strengthen organic breeding, it is important to know the state of the art of existing initiatives, programs and networks of organic breeding and breeding for organic, and in what ...
Messmer, Monika, Nuijten, Edwin, Vonzun, Seraina   +2 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Escuela de campo de agricultores para el fitomejoramiento participativo del boniato (Ipomoea batatas (L.) Lam.). Farmer´s Field School for the sweet potato (Ipomoea batatas (L.) Lam.) participatory breeding.

Agrisost, 2013
Resumen.Se presenta una Escuela de Campo para capacitar a los agricultores de sub urbanos en el Fitomejoramiento Participativo del boniato. En su concepción se emplearon métodos del nivel teórico (análisis – síntesis, inducción - deducción, histórico y ...
Mario Díaz López
doaj  

Seeds of resilience: the contribution of commons-based plant breeding and seed production to the social-ecological resilience of the agricultural sector

International Journal of Agricultural Sustainability, 2022
Building resilience in food systems is a priority to meet societal challenges such as climate change and biodiversity loss. However, there has been little systematic research on the role of seed production in fostering agroecological resilience.
Lea Kliem, Stefanie Sievers-Glotzbach
doaj   +1 more source

Breeding Ox-heart Tomato Populations through Participatory Plant Breeding in Italy

, 2021
[ES] El Mejoramiento Genético Participativo y Evolutivo ofrece una alternativa práctica al mejoramiento convencional centralizado y tiene como principales objetivos aumentar la participación de los agricultores y desarrollar materiales genéticos adaptados a condiciones pedo-climáticas específicas, sobre todo para aquellas ligadas a la agricultura ...
openaire   +3 more sources

Evaluation of sweetpotato (Ipomoea batatas (L.) Lam.) germplasm from north-eastern Uganda through a Farmer Participatory Approach [PDF]

, 2002
Ugandan farmers grow many landrace sweetpotato varieties, but some of these are relatively low yielding and susceptible to pests. The objective of the present research was to involve farmers in a large-scale assessment of Ugandan farmers’ varieties to ...
Abidin, P.E., Carey, E.E., Eeuwijk, F.A., van, Hermann, M., Stam, P., Struik, P.C., Zhang, D.P.   +6 more
core   +2 more sources