Results 71 to 80 of about 32,859 (307)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

PARTAGE DES CONNAISSANCES ENTRE AGRICULTEURS ET CHERCHEURS POUR CREER DES INNOVATIONS VARIETALES. LEÇONS DES PROGRAMMES DE SELECTION PARTICIPATIVE DU SORGHO CONDUITS DANS LA REGION NORD DU NICARAGUA [PDF]

open access: yes, 2010
N° ISBN - 978-2-7380-1284-5International audienceSharing knowledge between farmers and scientists for creating varietal innovations: lessons from participatory sorghum breeding programs managed in the northern region of Nicaragua.
Aguirre Acuña, Silvio   +6 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Report on quality characteristics of varieties to be used in organic farming [PDF]

open access: yes, 2007
The key questions which will be addressed in this report are: • Which variety characteristics are important for organic farming and are they different from conventional farmers demand? • What is an “appropriate“ variety for organic farming?
Micheloni, C., Plakolm, G.
core  

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

SHiNeMaS: a web tool dedicated to seed lots history, phenotyping and cultural practices

open access: yesPlant Methods, 2020
Motivation In 2005, researchers from the French National Research Institute for Agriculture, Food and Environment (Institut national de recherche pour l’agriculture, l’alimentation et l’environnement, INRAE) started a collaboration with the French ...
Yannick De Oliveira   +8 more
doaj   +1 more source

IDENTIFYING APPROPRIATE GERMPLASM FOR PARTICIPATORY BREEDING: AN EXAMPLE FROM THE CENTRAL VALLEYS OF OAXACA, MEXICO [PDF]

open access: yes
Identifying the appropriate germplasm to be improved is a key component of any participatory breeding effort because of its implications for impacts on social welfare and genetic diversity. This paper describes a method developed to select a subset of 17
Aguirre, Alfonso   +6 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Participatory plant breeding

open access: yes, 2016
Participatory breeding is a collective mode of genetic improvement of plants which brings together different stakeholders, including researchers, farmers, facilitators, etc. This participatory approach supplements the limits of the delegating mode of plant breeding established post-war in Europe, mode in which research and innovation were delegated by ...
Martineau, Lena   +2 more
openaire   +1 more source

Assessing the impact of participatory research in rice breeding on poor rice farming households with emphasis on women farmers: a case study in eastern Uttar Pradesh, India [PDF]

open access: yes, 2016
For the past years since the Consultative Group of International Agricultural Research (CGIAR) Systemwide Initiative on Participatory Research and Gender Analysis (PRGA) was initiated, guides for impact assessment of PRGA have been developed (Lilja and
Atlin, Gary   +4 more
core  

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