Results 141 to 150 of about 4,502,161 (251)

A Hybrid Hierarchical Framework for Quantifying Mechanical Markers in Atherosclerotic Disease Progression: A New Approach for Diagnosis and Risk Assessment

Advanced Science, EarlyView.
The mechanobiological basis of atherosclerotic progression and its contribution to spatial and temporal heterogeneity remain incompletely understood. Spatially resolved AFM measurements revealed that plaque formation and distinct regions (cap fibrosis, intimal fibrosis, and lipid‐rich core) exhibit heterogeneous elastic modulus and viscoelastic ...
Yidan Zhou, Zhuo Chang, Xianjun Wu, Sijie Wang, Yuzhi Zhang, Hao Zhang, Haoyu Xu, Ruining Peng, Zhe Wang, Huiyun Xu, Yu Liu, Guangkui Xu, Nu Zhang, Hui Yang   +13 more
wiley   +1 more source

Application of particle image velocimetry to wind turbine wakes [PDF]

, 1993
Wind turbine performance is critically dependent on the geometry of the rotor wake. Acquisition of detailed wake data is of major importance for further development of wind turbine studies.
Whale, J.
core  

Acoustically Activatable Drug‐Loaded Nanodroplets for Mechanochemical Therapy in Solid Tumors

Advanced Science, EarlyView.
Microfluidically fabricated drug‐loaded nanodroplets are sequentially activated by dual‐frequency ultrasound through acoustic droplet vaporization followed by bubble collapse, enabling spatially controlled drug release and mechanical tumor fractionation, resulting in synergistic mechanochemotherapy and prolonged survival.
Tiran Bercovici, Mike Bismuth, Meir Goldsmith, Dan Peer, Tali Ilovitsh   +4 more
wiley   +1 more source

Radioactive ion beam range adaptation in mouse tumors using in-beam PET

Communications Medicine
Background Treatment adaptation is particularly critical in particle therapy, where even small range deviations can compromise target coverage or lead to unintended dose delivered to surrounding healthy tissues. In-beam positron emission tomography (PET)
Martina Moglioni, Tamara Vitacchio, Francesco Evangelista, Munetaka Nitta, Daria Boscolo, Giulio Lovatti, Olga Sokol, Emma Haettner, Sivaji Purushothaman, Walter Tinganelli, Christian Graeff, Uli Weber, Christoph Schuy, Andreas Bückner, Gabriele Corbetta, Leonard Doyle, Lennart Volz, Maria Chiara Martire, Tim Wagner, Alexander Helm, Collin Werkheiser, Daria Kostyleva, Rinku Prajapat, Suraj Kumar Singh, Elena Rocco, Jonathan Bortfeldt, Peter G. Thirolf, Christoph Scheidenberger, Katia Parodi, Marco Durante   +29 more
doaj   +1 more source

Vine‐Inspired Soft Robotics: Materials, Actuations, and Emerging Applications

Advanced Science, EarlyView.
Vine‐inspired robots grow from the tip, enabling navigation through confined spaces with minimal disturbance. This Review summarizes material and actuation strategies for vine‐inspired growth, key functions including steering, retraction, attachment, branching, and variable stiffness, and emerging applications spanning medical intervention, confined ...
Jiahao Wu, Xingyun Liu, Fangzhou Wang, Huili Ren, Chaojun Zhang, Ziyu Ren, Zunqi Liu, Jing Li   +7 more
wiley   +1 more source

Prospective Registry and Meta‐Analysis of Particle Therapy for Hepatocellular Carcinoma: Clinical Outcomes and Real‐World Impact

Cancer Medicine
Background and Aims This study aimed to evaluate the clinical efficacy of particle therapy for hepatocellular carcinoma (HCC) by integrating a prospective registry and a systematic meta‐analysis.
Masashi Mizumoto, Kei Shibuya, Kazuki Terashima, Hiromitsu Iwata, Takashi Saito, Shingo Toyama, Takashi Ogino, Masao Murakami, Tatsuya Ohno, Yoshitaka Sato, Tetsuo Akimoto, Hiroyuki Katoh, Masaru Wakatsuki, Takahiro Waki, Norio Katoh, Fuki Koizumi, Masayuki Araya, Tsuyoshi Onoe, Masaru Takagi, Tomoaki Okimoto, Hiroyuki Ogino, Haruko Numajiri, Yoshiyuki Shioyama, Takayuki Hashimoto, Hisateru Ohba, Shoji Kubo, Kiyoshi Hasegawa, Kazushi Maruo, Hidefumi Aoyama, Hideyuki Sakurai   +29 more
doaj   +1 more source

Beam Dynamics Design of a Multi-Ion RFQ for Medical Application

Applied Sciences
Particle radiotherapy based on the medical accelerator is emerging as a major treatment for cancer. To enhance the clinical flexibility of particle radiotherapy and further promote the use of medical accelerators, the Shanghai Institute of Applied ...
Xinran Wang, Guiling Cao, Wenzhi Zhang
doaj   +1 more source

Optimization and verification of image reconstruction for a Compton camera towards application as an on-line monitor for particle therapy

, 2017
Particle therapy is an advanced cancer therapy that uses a feature known as the Bragg peak, in which particle beams suddenly lose their energy near the end of their range. The Bragg peak enables particle beams to damage tumors effectively.
Kataoka, (Waseda University) Jun, 485867, 485868, 長尾 悠人, 485861, 485862, Kurita, Keisuke, 485860, 485865, 485866, Tagawa, (Waseda University) Leo, 485863, Kimura, (Nagoya Proton Therapy Center) Mitsuhiro, 485864, 山口 充孝, Mochizuki, (Waseda University) Saku, Kawachi, Naoki, 河地 有木, 485858, 485859, 485856, 485857, Yamaguchi, Mitsutaka, 485854, 485855, 栗田 圭輔, Kishimoto, (Waseda University) Aya, Taya, (Waseda University) Takanori, Toshito, (Nagoya Proton Therapy Center) Toshiyuki, Nagao, Yuto, K. Kurita, L. Tagawa, Y. Nagao, S. Mochizuki, M. Yamaguchi, M. Kimura, N. Kawachi, A. Kishimoto, T. Toshito, T. Taya, J. Kataoka   +40 more
core   +1 more source

Early‐Life Manganese Overexposure Activates Microglial Phagocytosis through the YY1/TREM2 Axis Leading to Hippocampal Synaptic Remodeling in Mice

Advanced Science, EarlyView.
Early‐life manganese exposure induces behavioral deficits and aberrant hippocampal synaptic remodeling by enhancing microglial phagocytosis in young adult male mice. Mechanistically, manganese promotes Yin Yang 1 (YY1)/triggering receptor expressed on myeloid cells 2 (TREM2) signaling through enhanced HIF1α‐mediated transcription and suppressed SMURF2 ...
Keyu Chen, Bin He, Kuan Liu, Zhuo Ma, Bin Xu   +4 more
wiley   +1 more source

Heavy charged particle beam therapy and related new radiotherapy technologies: The clinical potential, physics and technical developments required to deliver benefit for patients with cancer. [PDF]

Br J Radiol, 2020
Kirkby KJ, Kirkby NF, Burnet NG, Owen H, Mackay RI, Crellin A, Green S.   +6 more
europepmc   +1 more source