Keeping It Native: Non‐Denaturing Approaches to Top‐Down Protein Mass Spectrometry
ABSTRACT Top‐down proteomics and top‐down mass spectrometry approaches provide direct characterization of proteoforms; the specific molecular forms of proteins, including post‐translational modifications, truncations, alternative splicing, and sequence variants.
Michael Xiao +3 more
wiley +1 more source
Radiation shielding behavior of B4C‐reinforced UHMWPE composites. ABSTRACT The present study investigates the radiation shielding performance of ultra‐high molecular weight polyethylene (UHMWPE) composites reinforced with varying boron carbide (B4C) contents against low‐energy X‐rays through combined experimental and computational approaches.
Elif Altındaş +4 more
wiley +1 more source
A Target-Specific, "Eco-Friendly" Experimental Setup for Small Field Proton Irradiation. [PDF]
Colizzi I +4 more
europepmc +1 more source
Neural Representation Learning for Compact and Efficient Modeling of Monte Carlo Phase Space Data. [PDF]
Charyyev S +4 more
europepmc +1 more source
Shielding assessment for multi-ion radiotherapy based on ion-specific dose-defined workloads. [PDF]
Lee US +6 more
europepmc +1 more source
Scheme 1. Schematic illustration of the synthesis and therapeutic evaluation of PLA‐g‐PAO microspheres (PLA‐g‐PAO‐Ms). Monodisperse PLA microspheres (PLA‐Ms) were initially fabricated via microfluidic technology. Surface grafting of acrylonitrile monomers was subsequently achieved through radiation‐induced graft polymerization, followed by ...
Xingliang Liu +7 more
wiley +1 more source
Particle Arc Therapy in Cancer Radiotherapy: A Scoping Review of Feasibility and Dosimetric Evidence. [PDF]
Neumann I +4 more
europepmc +1 more source
Expert consensus on clinical trial design guidelines for FLASH radiotherapy
• FLASH radiotherapy has emerged as a transformative technology due to the underlying FLASH effect. • As FLASH radiotherapy moves toward clinical application, establishing standardized trial design principles is critical. • This expert consensus provides a roadmap for rigorous clinical evaluation of FLASH radiotherapy, accelerating safe translation of ...
Hui Luo +9 more
wiley +1 more source
Study of prompt gamma and neutron emission for real-time range verification in proton and carbon-ion therapy. [PDF]
Bellotti ES +6 more
europepmc +1 more source
Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux +6 more
wiley +1 more source

