Results 91 to 100 of about 223,064 (315)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Remaining useful life prognostic of power metal oxide semiconductor field effect transistor based on improved particle filter algorithm

open access: yesAdvances in Mechanical Engineering, 2017
The power metal oxide semiconductor field effect transistor is used extensively in analog circuits and digital circuits. However, it is also the highest failure rate component in the power electronics system.
Lifeng Wu   +3 more
doaj   +1 more source

An unscented Kalman filter for freeway traffic estimation [PDF]

open access: yes, 2006
This paper addresses the problem of freeway tra±c flow estimation. The freeway is considered as a network of components representing different freeway stretches called segments.
HEGYI, A   +8 more
core   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Logical Particle Filtering

open access: yes, 2008
In this paper, we consider the problem of filtering in relational hidden Markov models. We present a compact representation for such models and an associated logical particle filtering algorithm. Each particle contains a logical formula that describes a set of states.
Zettlemoyer, Luke S.   +2 more
openaire   +4 more sources

Probability hypothesis density filtering for real-time traffic state estimation and prediction [PDF]

open access: yes, 2013
The probability hypothesis density (PHD) methodology is widely used by the research community for the purposes of multiple object tracking. This problem consists in the recursive state estimation of several targets by using the information coming from an
El Faouzi, Nour Eddin   +9 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Visual object tracking based on Motion-Adaptive Particle Filter under complex dynamics

open access: yesEURASIP Journal on Image and Video Processing, 2017
This paper presents a novel particle filter called Motion-Adaptive Particle Filter (MAPF) to track fast-moving objects that have complex dynamic movements.
Songxiao Cao, Xuanyin Wang, Ke Xiang
doaj   +1 more source

Challenges with bearings only tracking for missile guidance systems and how to cope with them. [PDF]

open access: yes, 2010
This paper addresses the problem of closed loop missile guidance using bearings and target angular extent information. Comparison is performed between particle filtering methods and derivative free methods.
Mihaylova, Lyudmila   +2 more
core  

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