Results 71 to 80 of about 223,064 (315)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Split-Gaussian particle filter [PDF]
2015 23rd European Signal Processing Conference (EUSIPCO), 2015 Publication in the conference proceedings of EUSIPCO, Nice, France ...
Juho Kokkala, Simo Särkkä
openaire +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Particle Swarm Optimization Artificial Immune Particle Filter
工程科学与技术, 2013 :To solve the particle weights degradation and sample impoverishment problems in particle filter which was used in non-Gaussian nonlinear systems, a new kind of particle filter was proposed.
杜正聪, 冯大海, 牛高远
doaj
Deteksi dan Pelacakan Wajah Berdasarkan Warna Kulit Menggunakan Partikel Filter
Jurnal Rekayasa Elektrika, 2018 Face detection and tracking are one of the areas which always in progress in many applications such as security system, biometric and so on. However, face detection and tracking can become a complex problem when it is done in real time condition.
Budi Sugandi
doaj +1 more source
Variance estimation in the particle filter [PDF]
, 2018 This paper concerns numerical assessment of Monte Carlo error in particle filters. We show that by keeping track of certain key features of the genealogical structure arising from resampling operations, it is possible to estimate variances of a number of
N Whiteley +5 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
IEEE Transactions on Signal ProcessingIn cognitive systems, recent emphasis has been placed on studying the cognitive processes of the subject whose behavior was the primary focus of the system's cognitive response. This approach, known as inverse cognition, arises in counter-adversarial applications and has motivated the development of inverse Bayesian filters.
Himali Singh +2 more
openaire +2 more sources
, 2015 The robust estimation of dynamically changing features, such as the position of prey, is one of the hallmarks of perception. On an abstract, algorithmic level, nonlinear Bayesian filtering, i.e. the estimation of temporally changing signals based on the history of observations, provides a mathematical framework for dynamic perception in real time ...
Kutschireiter, Anna +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source