Results 71 to 80 of about 2,224,405 (277)
A Rapid and Sensitive Salmonella Biosensor Based on Viscoelastic Inertial Microfluidics
Sensors, 2020 Salmonella is a main cause of foodborne illnesses and rapid screening of Salmonella is the key to prevent Salmonella outbreaks, however available detection methods either require a long time, or need complex pretreatment, or have low sensitivity. In this
Lan Yao +5 more
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Micromachines, 2016 Electrokinetic manipulation refers to the control of particle and cell motions using an electric field. It is an efficient technique for microfluidic applications with the ease of operation and integration. It, however, suffers from an intrinsic drawback
Lin Zhu +6 more
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A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Numerical Simulation for Dual Solid Particle Separation Using Fluidized Bed
Engineering ProceedingsParticle separation is a common process in various industries, particularly in mineral processing. Therefore, this research aimed to evaluate the performance of separation method using fluidized bed. The evaluation was performed using silica gel particle
Muhammad Lutfil Amin, Nur Ikhwan
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Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Cell Separation in a Water-drop-shaped Deterministic Lateral Displacement Device [PDF]
Journal of Applied Fluid MechanicsOwing to continuous advancements in microfluidic technology, deterministic lateral displacement (DLD) chips have been successfully applied to the separation of red blood cells (RBCs) and circulating tumour cells (CTCs).
J. W. Qu +4 more
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FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
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KONA Powder and Particle JournalIn KONA 2022, the fundamentals of two- and multidimensional particle size distributions were introduced. The next question in the field of two- and multidimensional distributions addresses their application to describe a particle process, e.g ...
Edgar Schach +10 more
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source