Results 51 to 60 of about 196,401 (259)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Study on microstructure and properties of pure tantalum TIG joints

open access: yesHanjie xuebao
A study on the microstructure, mechanical properties, and heat treatment process of pure tantalum TIG joints was conducted. Industrial computed tomography (CT), OM, and SEM were used to characterize the microstructure of the joints, and a microhardness ...
Chao YAN   +3 more
doaj   +1 more source

Development of a TaN-Ce Machine Learning Potential and Its Application to Solid–Liquid Interface Simulations

open access: yesMetals
This study develops a machine learning potential (MLP) based on the Moment Tensor Potential (MTP) method for the TaN-Ce system. This potential is employed to investigate the interfacial structure and wetting behavior between liquid Ce and solid TaN ...
Yunhan Zhang   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

ASSEMBLING SOME PARTS BY COLD PLASTIC WELDING [PDF]

open access: yesFiabilitate şi Durabilitate, 2021
This paper presents research on the non-removable assembly by cold plastic welding of parts made of materials of different nature. In this sense, cylindrical samples were made of S235 which were assembled by pressing with aluminum intermediate plate. 2
Florin CIOFU, Alin NIOAŢĂ
doaj  

Enhancing the Yield of a Lab-on-a-Disk-Based Single-Image Parasite Quantification Device

open access: yesMicromachines, 2023
The recently proposed single-image parasite quantification (SIMPAQ) platform based on a Lab-on-a-Disc (LOD) device was previously successfully tested in field conditions, demonstrating its efficiency in soil-transmitted helminth (STH) egg detection and ...
Vyacheslav R. Misko   +5 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Three-Dimensional Numerical Simulation of Particle Focusing and Separation in Viscoelastic Fluids

open access: yesMicromachines, 2020
Particle focusing and separation using viscoelastic microfluidic technology have attracted lots of attention in many applications. In this paper, a three-dimensional lattice Boltzmann method (LBM) coupled with the immersed boundary method (IBM) is ...
Chen Ni, Di Jiang
doaj   +1 more source

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