Results 41 to 50 of about 196,401 (259)

Hydrodynamic Microparticle Separation Mechanism Using Three-Dimensional Flow Profiles in Dual-Depth and Asymmetric Lattice-Shaped Microchannel Networks

Micromachines, 2019
We herein propose a new hydrodynamic mechanism of particle separation using dual-depth, lattice-patterned asymmetric microchannel networks. This mechanism utilizes three-dimensional (3D) laminar flow profiles formed at intersections of lattice channels ...
Takuma Yanai, Takatomo Ouchi, Masumi Yamada, Minoru Seki   +3 more
doaj   +1 more source

A Rapid and Sensitive Salmonella Biosensor Based on Viscoelastic Inertial Microfluidics

Sensors, 2020
Salmonella is a main cause of foodborne illnesses and rapid screening of Salmonella is the key to prevent Salmonella outbreaks, however available detection methods either require a long time, or need complex pretreatment, or have low sensitivity. In this
Lan Yao, Lingyan Zheng, Gaozhe Cai, Siyuan Wang, Lei Wang, Jianhan Lin   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Elasto-Inertial Focusing Mechanisms of Particles in Shear-Thinning Viscoelastic Fluid in Rectangular Microchannels

Micromachines, 2022
Growth of the microfluidics field has triggered numerous advances in focusing and separating microparticles, with such systems rapidly finding applications in biomedical, chemical, and environmental fields.
Mohammad Moein Naderi, Ludovica Barilla, Jian Zhou, Ian Papautsky, Zhangli Peng   +4 more
doaj   +1 more source

Acoustofluidic separation of cells and particles

Microsystems & Nanoengineering, 2019
AbstractAcoustofluidics, the integration of acoustics and microfluidics, is a rapidly growing research field that is addressing challenges in biology, medicine, chemistry, engineering, and physics. In particular, acoustofluidic separation of biological targets from complex fluids has proven to be a powerful tool due to the label-free, biocompatible ...
Mengxi Wu, Adem Ozcelik, Joseph Rufo, Zeyu Wang, Rui Fang, Tony Jun Huang   +5 more
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Simulation study on the influence of initial density distribution of laser ionized plasma on the ion extraction characteristics

AIP Advances
In isotope concentration technology, ion extraction current and ion extraction efficiency are the key factors to measure the efficiency of the isotope concentration.
Xing Chen, Xiao-Yong Lu, Lu Cai
doaj   +1 more source

Biomedical Applications of Microfluidic Devices: A Review

Biosensors, 2022
Both passive and active microfluidic chips are used in many biomedical and chemical applications to support fluid mixing, particle manipulations, and signal detection. Passive microfluidic devices are geometry-dependent, and their uses are rather limited.
Ghazaleh Gharib, İsmail Bütün, Zülâl Muganlı, Gül Kozalak, İlayda Namlı, Seyedali Seyedmirzaei Sarraf, Vahid Ebrahimpour Ahmadi, Erçil Toyran, Andre J. van Wijnen, Ali Koşar   +9 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Computational Inertial Microfluidics: Optimal Design for Particle Separation

Fluids, 2022
Following the emergence of many blood transfusion-associated diseases, novel passive cell separation technologies, such as microfluidic devices, are increasingly designed and optimized to separate red blood cells (RBCs) and white blood cells (WBCs) from ...
Suvash C. Saha, Isabella Francis, Tanya Nassir   +2 more
doaj   +1 more source