Results 191 to 200 of about 7,641,603 (287)
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Support Size of <i>ε</i>-Capacity-Achieving Inputs for the Amplitude-Constrained AWGN Channel. [PDF]
Barletta L, Dytso A.
europepmc +1 more source
Título de empréstito al portador de Riegos y Saltos de Almería, Sociedad Civil Particular Anónima
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
System failure and health inequity in plain sight: Menopause, misdiagnosis, and the cost to women's physical, social, economic, mental health and wellbeing. [PDF]
Michel J, Bigler C, Diallo D, Ardojan K.
europepmc +1 more source

