Results 201 to 210 of about 19,145,566 (340)
The wood and the trees: estimands in cluster randomised trials. [PDF]
Hooper R, Hemming K, Li F.
europepmc +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
The <i>REAL</i> journey: a meaning-oriented approach to moral injury care. [PDF]
Smigelsky MA.
europepmc +1 more source
Particular remisión de V. capilla particular.
[ES] Definición del término Particular remisión de V. capilla particular. en el diccionario Dicter. [EN] Definition of the word Particular remisión de V. capilla particular. in the dictionary Dicter.
openaire +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
A reassessment of the role of high <i>x</i> data on the MSHT global PDF fit. [PDF]
Harland-Lang LA +3 more
europepmc +1 more source
Particular remisión de V. reloj particular.
[ES] Definición del término Particular remisión de V. reloj particular. en el diccionario Dicter. [EN] Definition of the word Particular remisión de V. reloj particular. in the dictionary Dicter.
openaire +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source

