Results 91 to 100 of about 1,911,864 (297)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Policy Guide For Municipal Leaders and Legislators [PDF]
, 2013 This Guide for Municipal Leaders and Legislators, is a companion to the full 2013 State of Our Estuaries Report, and focuses more specifically on what state and local leaders can do to improve environmental conditions in the estuaries.
Piscataqua Region Estuaries Partnership
core +1 more source
Implementing CSR through partnerships: Understanding the selection, design and institutionalisation of nonprofit-business partnerships [PDF]
, 2008 Partnerships between businesses and nonprofit organisations are an increasingly prominent element of corporate social responsibility implementation. The paper is based on two in depth partnership case studies (Earthwatch-Rio Tinto and Prince’s Trust ...
Crane, A, Seitanidi, MM
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Fitness to Drive Policy in Inpatient Setting: Findings of QI Project
BJPsych OpenAims Background: Nature and degree of mental illness can impair abilities of patients to drive safely which puts their own safety and safety of others at risk.
Sajid Mahmood +4 more
doaj +1 more source
The Partnership Bill 2003: unnecessary tinkering or much-needed reform? [PDF]
, 2005 Purpose - To examine the nature and merits of the proposed changes to partnership law contained in the draft Partnership Bill published in the Law Commission's Partnership Law Report (2003).
Berry, E
core
A ‘quiet revolution’? The impact of Training Schools on initial teacher training partnerships [PDF]
, 2006 This paper discusses the impact on initial teacher training of a new policy initiative in England: the introduction of Training Schools. First, the Training School project is set in context by exploring the evolution of a partnership approach to initial ...
AA Espie +71 more
core +2 more sources
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Health Research Policy and Systems, 2018 Background Cross-sectoral, multidisciplinary partnership research is considered one of the most effective means of facilitating research-informed policy and practice, particularly for addressing complex problems such as chronic disease.
Sonia Wutzke +9 more
doaj +1 more source
State of Our Estuaries 2009 [PDF]
, 2009 The 2009 State of the Estuaries Report describes the status and trends of 12 primary indicators tracked by PREP. For each key indicator, the report provides the monitoring question and answer, PREP management goal, information on relevance, and an ...
Piscataqua Region Estuaries Partnership
core +2 more sources