Results 71 to 80 of about 1,911,864 (297)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Bangladeshi Immigrants in Buffalo [PDF]

, 2016
Bangladeshi immigrants have relocated to Buffalo, New York, at a pace that has surprised many. The size of Buffalo’s Bangladeshi population is unknown. The U.S. Census estimates that 316 Bangladeshis live in Buffalo, but Liberty Yellow Taxi alone employs
Partnership for the Public Good
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

State of India's Birds 2023: A framework to leverage semi‐structured citizen science for bird conservation

Ecosphere
Birds and their habitats are threatened with extinction around the world. Regional assessments of the “State of Birds” are a vital means to prioritize data‐driven conservation action by informing national and global policy.
Ashwin Viswanathan, Karthik Thrikkadeeri, Pradeep Koulgi, Praveen J., Arpit Deomurari, Ashish Jha, Ashwin Warudkar, Kulbhushansingh Suryawanshi, M. D. Madhusudan, Monica Kaushik, Naman Goyal, Rajah Jayapal, Suhel Quader, Sutirtha Dutta, Tarun Menon, Vivek Ramachandran   +15 more
doaj   +1 more source

A Plan that Bears Fruit: A Community Land Trust and Other Tools For Neighborhood Revitalization in the Fruit Belt [PDF]

, 2016
On December 1, 2015, the City of Buffalo’s Common Council passed a resolution placing a moratorium on the sale of city-owned lots in the Fruit Belt neighborhood.
Partnership for the Public Good
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

The Network for Calibration and Validation in Earth Observation (NCAVEO) 2006 field campaign

, 2008
This paper describes a remote sensing field campaign undertaken by the Network for Calibration and Validation in Earth Observation (NCAVEO) in southern England in June 2006.
Milton, E.J., NCAVEO Partnership
core  

Raising the Minimum Wage: Key Facts and Figures [PDF]

, 2014
In New York State, roughly 37% or workers earn low wages (less than $15 per hour, or $31,200 per year). In Erie County, the percentage is 41% (159,800 of 393,600 wage-earning workers). 94% of low wage workers in New York State are age 20 or over.
Partnership for the Public Good
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Malaria case investigation with reactive focal testing and treatment: operational feasibility and lessons learned from low and moderate transmission areas in Amhara Region, Ethiopia

Malaria Journal, 2018
Background When malaria transmission is very low, investigation of passively detected malaria cases and reactive focal testing and treatment (FTAT) in the case and neighbouring households can identify and contain the source and spread of infections ...
Pooja Bansil, Asnakew K. Yeshiwondim, Caterina Guinovart, Belendia Serda, Callie Scott, Berhane H. Tesfay, Adem Agmas, Belay Bezabih, Melkamu T. Zeleke, Girma S. Guesses, Asmamaw L. Ayenew, Worku M. Workie, Duncan Earle, Rick W. Steketee, Asefaw Getachew   +14 more
doaj   +1 more source