Results 71 to 80 of about 1,901,965 (297)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Why Buffalo Needs Inclusionary Zoning: Affordability, Job Access, Inclusion, and Quality Housing [PDF]
, 2017 Buffalo’s housing market faces four severe challenges: affordability, job access, inclusiveness, and quality. Inclusionary zoning is a proven tool for addressing all four issues.
Partnership for the Public Good
core +1 more source
Implementing CSR through partnerships: Understanding the selection, design and institutionalisation of nonprofit-business partnerships [PDF]
, 2008 Partnerships between businesses and nonprofit organisations are an increasingly prominent element of corporate social responsibility implementation. The paper is based on two in depth partnership case studies (Earthwatch-Rio Tinto and Prince’s Trust ...
Crane, A, Seitanidi, MM
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
EcosphereBirds and their habitats are threatened with extinction around the world. Regional assessments of the “State of Birds” are a vital means to prioritize data‐driven conservation action by informing national and global policy.
Ashwin Viswanathan +15 more
doaj +1 more source
Malaria Journal, 2018 Background When malaria transmission is very low, investigation of passively detected malaria cases and reactive focal testing and treatment (FTAT) in the case and neighbouring households can identify and contain the source and spread of infections ...
Pooja Bansil +14 more
doaj +1 more source
Bangladeshi Immigrants in Buffalo [PDF]
, 2016 Bangladeshi immigrants have relocated to Buffalo, New York, at a pace that has surprised many. The size of Buffalo’s Bangladeshi population is unknown. The U.S. Census estimates that 316 Bangladeshis live in Buffalo, but Liberty Yellow Taxi alone employs
Partnership for the Public Good
core +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
A Federated Data Linkage Strategy to Support Population Health Research in Canada
International Journal of Population Data Science, 2017 Objectives Canada has established a pan-Canadian cohort with over 300,000 volunteer participants aged 35-69, to support research on cancer and chronic disease. A key feature of the cohort is that participants have consented to link their cohort data with
Tanya Flanagan +2 more
doaj +1 more source
The Network for Calibration and Validation in Earth Observation (NCAVEO) 2006 field campaign
, 2008 This paper describes a remote sensing field campaign undertaken by the Network for Calibration and Validation in Earth Observation (NCAVEO) in southern England in June 2006.
Milton, E.J., NCAVEO Partnership
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