Results 91 to 100 of about 51,758 (256)

Optimisation of an extraction technique of fish allergens suitable for detection and diagnosis

open access: yesCzech Journal of Food Sciences, 2017
An optimised protocol for the extraction of allergenic proteins in fish was developed. Twelve existing or modified extraction buffers were evaluated based on the amount and quality of obtained 12 kDa IgG-binding protein (major fish allergen parvalbumin ...
Jiaju Ma   +3 more
doaj   +1 more source

In vivo acceleration of heart relaxation performance by parvalbumin gene delivery

open access: yes, 2001
Defective cardiac muscle relaxation plays a causal role in heart failure. Shown here is the new in vivo application of parvalbumin, a calcium-binding protein that facilitates ultrafast relaxation of specialized skeletal muscles.
Margaret V. Westfall   +19 more
core   +1 more source

The Origins of Ploem's Filter Cube: A Pandora's Box

open access: yesJournal of Microscopy, EarlyView.
Abstract Ploem's filter cube, central to modern epifluorescence microscopy, integrates three matched optical components: an excitation filter, an emission filter, and a dichroic mirror. Together, these elements enable the separation of excitation and emission light paths, producing high‐contrast fluorescence images.
Jack Gordon   +3 more
wiley   +1 more source

Distribution Patterns of Three Molecularly Defined Classes of GABAergic Neurons Across Columnar Compartments in Mouse Barrel Cortex

open access: yesFrontiers in Neuroanatomy, 2019
The mouse somatosensory cortex is an excellent model to study the structural basis of cortical information processing, since it possesses anatomically recognizable domains that receive different thalamic inputs, which indicates spatial segregation of ...
Zsuzsanna Almási   +3 more
doaj   +1 more source

Activity of ventral hippocampal parvalbumin interneurons during anxiety. [PDF]

open access: yes
Anxiety plays a key role in guiding behavior in response to potential threats. Anxiety is mediated by the activation of pyramidal neurons in the ventral hippocampus (vH), whose activity is controlled by GABAergic inhibitory interneurons.
Nevian, Thomas   +9 more
core   +1 more source

Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 505-516, April 2025.
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer   +4 more
wiley   +1 more source

Application of Fluorescence Two-Dimensional Difference In-Gel Electrophoresis as a Proteomic Biomarker Discovery Tool in Muscular Dystrophy Research

open access: yesBiology, 2013
In this article, we illustrate the application of difference in-gel electrophoresis for the proteomic analysis of dystrophic skeletal muscle. The mdx diaphragm was used as a tissue model of dystrophinopathy.
Steven Carberry   +3 more
doaj   +1 more source

Physiological sharp wave-ripples and interictal events in vitro: What’s the difference?

open access: yes, 2014
Sharp wave-ripples and interictal events are physiological and pathological forms of transient high activity in the hippocampus with similar features.
Káli, Szabolcs   +7 more
core  

Parvalbumin expression identifies subicular principal cells with high projection specificity

open access: yes
The calcium-binding protein parvalbumin is an established marker for a subset of cortical inhibitory interneurons with similar biophysical features and connectivity.
Wozny, Christian   +11 more
core   +1 more source

Chronic silencing of subsets of cortical layer 5 pyramidal neurons has a long‐term influence on the laminar distribution of parvalbumin interneurons and the perineuronal nets

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 479-504, April 2025.
Chronic silencing of subsets of layer 5 projection neurons has distinct effects on the laminar distribution of PV interneurons and the perineuronal nets in the adult primary motor and somatosensory cortex. Abstract Neural networks are established throughout cortical development, which require the right ratios of glutamatergic and GABAergic neurons ...
Florina P. Szabó   +4 more
wiley   +1 more source

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