Results 101 to 110 of about 45,557 (210)

Brain‐Wide Mapping and Synaptic Localization of C1QL3 Using a Novel Epitope‐Tagged Knock‐In Mouse

Journal of Comparative Neurology, Volume 534, Issue 8, August 2026.
C1QL3 is a secreted adhesion molecule that acts as a key regulator of synaptic structure and function. We generated and validated a novel epitope‐tagged knock‐in mouse line (C1ql32HA) in which two hemagglutinin (HA) epitopes were inserted near the N‐terminus of the endogenous C1QL3 protein.
William P. Armstrong IV, James M. Salvatore, Matthew J. Sticco, Keaven Caro, J. Wesley Maddox, Angie Huang, Brenna C. McAllister, Christopher B. O'Connell, Siu‐Pok Yee, Amy Lee, Susanne Ressl, David C. Martinelli, Alexander C. Jackson   +12 more
wiley   +1 more source

Progressive myoclonus epilepsy in Down syndrome with Alzheimer's disease: An 11‐year longitudinal study and proposed diagnostic red flags

Epilepsia Open, Volume 11, Issue 4, Page 1200-1213, August 2026.
Abstract Objective Individuals with Down syndrome (DS) face an ultra‐high risk of Alzheimer's disease (AD). Within this continuum, Progressive Myoclonus Epilepsy (PME) has emerged as a marker of advanced neurodegeneration. Building on our 2014 characterization of this syndrome, we aimed to define its long‐term natural history and pathological substrate.
Giuseppe d'Orsi, Ezio Calò, Maria Teresa Di Claudio, Carmela Pia Ferro, Umberto Costantino, Elio Perrone, Raffaela Rita Latino   +6 more
wiley   +1 more source

Barbaloin Attenuates Cisplatin‐Induced Hippocampal Neurotoxicity by Suppressing Oxidative Stress, Neuroinflammation, and Apoptosis: In Vivo and In Silico Evidence

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Important Aloe vera phytonutrient, barbaloin, inhibits the neurotoxic effects of cisplatin on hippocampus, which involves reducing oxidative stress, neuroinflammation, and apoptosis, thereby restoring the balance of neurotransmitters and cognition. The generated docking structures with 100‐ns molecular dynamics simulations show stable energy‐minimized ...
Rahamat Unissa Syed, Rihab Akasha, Nancy Mohammad Elafandy, Sally Hassan Abobaker, Afrah Nashmi Al‐Shammari, Lama Abdullah Altwalah, Rawabi Mohammed Menwer Aldafeeri, Amira Ibrahim Mohammed Ahmed Alfaki, Mohd Sajjad Ahmad Khan, Ashgan A. Ahmed   +9 more
wiley   +1 more source

Decoding Brain Development and Function Through GABAergic Inhibitory Neurons

European Journal of Neuroscience, Volume 64, Issue 3, August 2026.
Interneuron subtype specification occurs case by case. Whereas some interneurons are specified very early, at the progenitor level, other interneurons develop final features during migration into the migratory stream or upon integration into specific cortical layers. The concept that interneuron specification can be significantly influenced by external
Renata Batista‐Brito, Christian Mayer, Mercedes Paredes, Carla G. Silva   +3 more
wiley   +1 more source

Cytoarchitecture and myeloarchitecture of the sheep auditory cortex

Journal of Anatomy, Volume 249, Issue 2, Page 233-246, August 2026.
This article describes the cyto‐ and myeloarchitecture of the sheep auditory cortex. It outlines a six‐layered cortical organization, with variations in cellular types and densities. The potential location of the primary auditory cortex is indicated by parvalbumin immunostaining.
Camille Pluchot, Mélody Morisse, Maryse Meurisse, Jean‐Marie Graïc, Elodie Chaillou, Scott A. Love   +5 more
wiley   +1 more source

Cerebellar structure and function abnormalities in 16p11.2 microduplication mice. [PDF]

Brain Commun
Hayes C, Halverson H, Keeran K, Tison K, Jacobo K, Karki A, Herring I, Tunuguntla SNS, Pace M, Doan B, Wen H, Klomp A, Lauffer M, Gaine ME, Parker KL, Williams AJ.   +15 more
europepmc   +1 more source

Correction: From Balance to Breakdown: striatal PV interneurons in Huntington's disease and Autism Spectrum Disorder. [PDF]

Front Cell Neurosci
Thabault M, Galvan L.
europepmc   +1 more source

Lewy Bodies Are Not Associated With Neuronal or Synaptic Loss in Dementia With Lewy Bodies. [PDF]

Neuropathol Appl Neurobiol
Hawksworth JI, Kirkby-Geddes E, Thom S, O'Neill J, Ikwue A, Wood L, Outeiro TF, Erskine D.   +7 more
europepmc   +1 more source

Not all that glitters is gold: off-target recombination in the somatostatin IRES-Cre mouse line labels a subset of fast-spiking interneurons

Frontiers in Neural Circuits, 2013
Hang eHu, John Z Cavendish, Ariel eAgmon
doaj   +1 more source

Allergenic Characterization of Parvalbumin, Tric l 1, From Atlantic cutlassfish, <i>Trichiurus lepturus</i>. [PDF]

Allergy Asthma Immunol Res
Park KH, Shin YJ, Lee YS, Sang M, Park JW, Jeong KY.   +5 more
europepmc   +1 more source