Results 121 to 130 of about 46,693 (216)

Muscarinic agonists for schizophrenia: Bridging preclinical evidence and clinical enthusiasm

British Journal of Pharmacology, Volume 183, Issue 19, Page 5701-5731, October 2026.
Abstract Antipsychotic drugs targeting dopamine receptors have been used to treat schizophrenia for decades, primarily alleviating positive symptoms such as hallucinations and delusions. However, they provide limited benefit for cognitive and negative symptoms—major contributors to poor outcomes—and are frequently associated with significant side ...
Brian J. Morris, Judith A. Pratt
wiley   +1 more source

Neural Cell Models of Specific Reading Disabilities: Identification of Cellular and Transcriptome Alterations

Genes, Brain and Behavior, Volume 25, Issue 5, October 2026.
Neural cell phenotypes were tested using cells derived from two pairs of siblings strongly discordant for reading—probands with severe RD and their strong‐reader siblings. We observed significant differences in outgrowth in the neurosphere assay using the neural precursor cells (NPCs) derived from the probands compared to cells from their strong‐reader
Cathy L. Barr, Karen G. Wigg, Yu Feng, Kirsten Blokland, Margaret Wilkinson, Elizabeth N. Kerr, Sharon L. Guger, Maureen W. Lovett, Lisa J. Strug, Ruth Oefner, Simone Benassi, Fred H. Gage, Maria C. Marchetto   +12 more
wiley   +1 more source

Molecular sensitization profiles and β-parvalbumin sensitization burden associated with clinical fish allergy in children. [PDF]

Front Immunol
Dal ST, Heydarova L, Sekerel BE.
europepmc   +1 more source

Correction: From Balance to Breakdown: striatal PV interneurons in Huntington's disease and Autism Spectrum Disorder. [PDF]

Front Cell Neurosci
Thabault M, Galvan L.
europepmc   +1 more source

Selective loss of primary cilia and neurotrophic signaling in G51D α-synuclein mice highlights a common pathway to Parkinson's disease. [PDF]

Proc Natl Acad Sci U S A
Lin YE, Jaimon E, Kim Y, Loftman A, Vijayakumaran A, Belfort BDW, Chiang CY, Arenkiel BR, Zoghbi HY, Pfeffer SR.   +9 more
europepmc   +1 more source

Lewy Bodies Are Not Associated With Neuronal or Synaptic Loss in Dementia With Lewy Bodies. [PDF]

Neuropathol Appl Neurobiol
Hawksworth JI, Kirkby-Geddes E, Thom S, O'Neill J, Ikwue A, Wood L, Outeiro TF, Erskine D.   +7 more
europepmc   +1 more source

Decoding Brain Development and Function Through GABAergic Inhibitory Neurons. [PDF]

Eur J Neurosci
Batista-Brito R, Mayer C, Paredes M, Silva CG.   +3 more
europepmc   +1 more source

Perineuronal nets preferentially surround parvalbumin interneurons in the prelimbic cortex: A rat and mouse comparison. [PDF]

Brain Res
Jenike AE, Brown TE, Impey S, Sorg BA, Aicher SA.   +4 more
europepmc   +1 more source

Asparagine Synthetase Deficiency: Neuropathological Evidence of Disrupted Cortical Development. [PDF]

JIMD Rep
Bobić M, Sedmak G, Bokulić E, Medenica T, Žigman T, Vinković BM, Antolović V, Kešin N, Lehman I, Škaričić A, Novoselec M, Mateševac J, Kalamar MK, Frković SH, Barić I, Ramadža DP.   +15 more
europepmc   +1 more source

Correction for Qiu et al., Parvalbumin gates chronic pain through the modulation of firing patterns in inhibitory neurons. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source