Results 21 to 30 of about 2,357 (169)
GABAA receptors containing δ subunits (δ-GABAARs) are GABA-gated ion channels with extra- and perisynaptic localization, strong sensitivity to neurosteroids (NS), and a high degree of plasticity.
Albert Miklos Barth +2 more
doaj +1 more source
Distinctive genetic markers of the central and southern populations of the northern anchovy Engraulis mordax were sought by electrophoretic techniques.
P Díaz-Jaime +2 more
doaj +1 more source
Parvalbumin neurons in the forebrain as revealed by parvalbumin-Cre transgenic mice
Neurons expressing the calcium-binding protein parvalbumin (PV) constitute an abundant subpopulation of GABAergic neurons in the cerebral cortex. However, PV is not unique to the GABAergic neurons of the forebrain, but is also expressed in a small number of pyramidal neurons and in a large number of thalamic neurons.
Chiyoko, Tanahira +6 more
openaire +2 more sources
Electrophoresis in native 7.5% polyacrylamide gel made in Tris-HCl and run in Tris-borate revealed three parvalbumin phenotypes in soluble proteins of white skeletal muscle of spotted snakehead Channa punctata. Parvalbumins (PV) were initially recognized
RIAZ AHMAD +3 more
doaj +1 more source
Allergic cross-reactivity – anew challenge for allergists?
Allergic cross-reactivity is an important epidemiological issue in all age groups. It is caused by a non-specific binding of both primary allergen as well as allergens causing secondary cross-reactivity by the same IgE antibodies.
Krzysztof Łukasz Piwowarek +3 more
doaj +1 more source
Reduction in parvalbumin expression not loss of the parvalbumin-expressing GABA interneuron subpopulation in genetic parvalbumin and shank mouse models of autism [PDF]
A reduction of the number of parvalbumin (PV)-immunoreactive (PV(+)) GABAergic interneurons or a decrease in PV immunoreactivity was reported in several mouse models of autism spectrum disorders (ASD). This includes Shank mutant mice, with SHANK being one of the most important gene families mutated in human ASD.
Filice, Federica +4 more
openaire +5 more sources
Multifactorial Modulation of Food-Induced Anaphylaxis
Prevalence of food-induced anaphylaxis increases progressively and occurs in an unpredictable manner, seriously affecting the quality of life of patients.
Sara Benedé +5 more
doaj +1 more source
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong +14 more
wiley +1 more source
ABSTRACT Variants in the CNTNAP2 gene, encoding the cell adhesion molecule CASPR2, have been identified as genetic risk factors for autism spectrum disorder (ASD). However, the mechanisms through which CNTNAP2 dysfunction alters circuit function remain unknown.
Krisztina Sáfár +10 more
wiley +1 more source
On the importance of including both sexes in animal studies – insights from home‐cage monitoring
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater +12 more
wiley +1 more source

