Results 21 to 30 of about 2,372 (180)

Ovarian cycle-linked plasticity of δ-GABAA receptor subunits in hippocampal interneurons affects γ oscillations in vivo

open access: yesFrontiers in Cellular Neuroscience, 2014
GABAA receptors containing δ subunits (δ-GABAARs) are GABA-gated ion channels with extra- and perisynaptic localization, strong sensitivity to neurosteroids (NS), and a high degree of plasticity.
Albert Miklos Barth   +2 more
doaj   +1 more source

Electrophoretic variation between the central and southern populations of the northern anchovy Engraulis mordax Girard 1854 (Engraulidae, Pisces) from Baja California, Mexico

open access: yesCiencias Marinas, 1999
Distinctive genetic markers of the central and southern populations of the northern anchovy Engraulis mordax were sought by electrophoretic techniques.
P Díaz-Jaime   +2 more
doaj   +1 more source

Parvalbumin neurons in the forebrain as revealed by parvalbumin-Cre transgenic mice

open access: yesNeuroscience Research, 2009
Neurons expressing the calcium-binding protein parvalbumin (PV) constitute an abundant subpopulation of GABAergic neurons in the cerebral cortex. However, PV is not unique to the GABAergic neurons of the forebrain, but is also expressed in a small number of pyramidal neurons and in a large number of thalamic neurons.
Chiyoko, Tanahira   +6 more
openaire   +2 more sources

Differences in Thermal Aggregability of Polymorphic Soluble Muscle Proteins of Channa punctata (Channidae: Channiformes)

open access: yesAsian Fisheries Science, 2007
Electrophoresis in native 7.5% polyacrylamide gel made in Tris-HCl and run in Tris-borate revealed three parvalbumin phenotypes in soluble proteins of white skeletal muscle of spotted snakehead Channa punctata. Parvalbumins (PV) were initially recognized
RIAZ AHMAD   +3 more
doaj   +1 more source

Allergic cross-reactivity – anew challenge for allergists?

open access: yesPediatria i Medycyna Rodzinna, 2015
Allergic cross-reactivity is an important epidemiological issue in all age groups. It is caused by a non-specific binding of both primary allergen as well as allergens causing secondary cross-reactivity by the same IgE antibodies.
Krzysztof Łukasz Piwowarek   +3 more
doaj   +1 more source

Reduction in parvalbumin expression not loss of the parvalbumin-expressing GABA interneuron subpopulation in genetic parvalbumin and shank mouse models of autism [PDF]

open access: yesMolecular Brain, 2016
A reduction of the number of parvalbumin (PV)-immunoreactive (PV(+)) GABAergic interneurons or a decrease in PV immunoreactivity was reported in several mouse models of autism spectrum disorders (ASD). This includes Shank mutant mice, with SHANK being one of the most important gene families mutated in human ASD.
Filice, Federica   +4 more
openaire   +5 more sources

Multifactorial Modulation of Food-Induced Anaphylaxis

open access: yesFrontiers in Immunology, 2017
Prevalence of food-induced anaphylaxis increases progressively and occurs in an unpredictable manner, seriously affecting the quality of life of patients.
Sara Benedé   +5 more
doaj   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

open access: yesAdvanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong   +14 more
wiley   +1 more source

Cysteine Redox State Governs the Condensation Pathway of Hendra Virus W Protein and Differentially Impacts Type I IFN and NF‐κB Signaling

open access: yesAdvanced Science, EarlyView.
The cysteine redox state of the Hendra virus W (WHeV) protein controls assembly into fibrils or amorphous aggregates, with residues 2–29 required for fibrillation. In cells, WHeV forms different types of nuclear condensates. Impaired ability to form redox‐sensitive, non‐filamentous condensates reduces WHeV inhibition of the NF‐κB pathway, while it ...
Frank Gondelaud   +12 more
wiley   +1 more source

Multiscale Circuit Architecture Associated With Memory Dysfunction in Temporal Lobe Epilepsy

open access: yesAdvanced Science, EarlyView.
A multiscale precision‐mapping framework reveals that memory impairment in temporal lobe epilepsy arises from the convergence of focal medial temporal pathology, strategic white matter disconnection, and limbic‐centered metabolic network dysfunction.
Jiajie Mo   +12 more
wiley   +1 more source

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