Results 61 to 70 of about 2,357 (169)

IHC_cFOS+Parvalbumin v1

open access: yes, 2023
Immunohistochemistry protocol for c-FOS and Parvalbumin co-staining of mouse brain tissue slices (30 microns thick).
openaire   +1 more source

Neurodevelopmental Consequences Induced by Early‐Life Lead Exposure Through Disruption of Neurotransmitter Pathways and Molecular Mechanisms: A Systematic Review

open access: yesDevelopmental Neurobiology, Volume 86, Issue 3, July 2026.
ABSTRACT Lead is a toxic heavy metal with significant health risks, as maternal lead exposure during pregnancy disrupts fetal neural development through placental transfer, leading to persistent neurological, developmental, and long‐term health consequences in the progeny.
P. Harshitha   +3 more
wiley   +1 more source

Epilepsy: Epidemiology, Molecular Pathogenesis, and Clinical Management

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Epilepsy is a heterogeneous and chronically evolving brain network disorder. This review integrates epidemiological burden, psychiatric comorbidities, and cyclic seizure patterns with multiscale pathogenic mechanisms, including ion‐channel dysfunction, synaptic transmission defects, neuroinflammation, metabolic and mitochondrial dysfunction, and ...
Jian Liu   +8 more
wiley   +1 more source

In rats, neurodevelopmental disorders induced by maternal hypoxia are associated with attenuated excitatory neurotransmission in the cingulate cortex

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 13, Page 3723-3742, July 2026.
Background and Purpose Maternal hypoxia is a recognised risk factor for neurodevelopmental disorders in offspring. Although rodent models of hypoxia have been reported, the detailed pathogenesis of maternal hypoxia‐induced neurodevelopmental disorders remains unclear.
Kentaro Tokudome   +6 more
wiley   +1 more source

Splice Type‐Specific Effects of Gαo Subunits on Cerebellar Anatomy and Synapse Formation

open access: yesJournal of Neurochemistry, Volume 170, Issue 7, July 2026.
Heterotrimeric Go alpha subunits are widely expressed in the brain to act as molecular switches. In this study we show that Gαo1 and Gαo2 affect cerebellar morphology and synapse formation in an opposite manner. While knockout of Gαo1 results in cerebellar hypoplasia and reduced synaptic input to Purkinje cells by VGLUT2‐positive brainstem climbing ...
Markus Höltje   +2 more
wiley   +1 more source

Circadian‐Related Serotonin/Melatonin Level Modulates Cisplatin Ototoxicity Susceptibility Depended on NOS3–NO Pathway

open access: yesJournal of Pineal Research, Volume 78, Issue 4, July 2026.
ABSTRACT Hearing impairment is attributed to factors such as age, genetic predisposition, and environmental influences, among which environmental factors are considered modifiable. Among various environmental factors, the role of poor lifestyle habits is particularly critical, yet the specific mechanisms by which they contribute to hearing damage ...
Siyu Qiu   +4 more
wiley   +1 more source

Interhemispheric Metabolic Effects of Transcranial Infrared Laser Stimulation of the Prefrontal Cortex

open access: yesHuman Brain Mapping, Volume 47, Issue 9, June 15, 2026.
Unilateral prefrontal TILS reliably increases ipsilateral cytochrome‐c‐oxidase and oxygenated hemoglobin, demonstrating dose‐dependent metabolic efficacy without adverse effects. Contralateral responses are asymmetric: changes emerge later and differ by stimulation side, with stronger right‐hemisphere effects after left‐sided TILS, suggesting ...
Patrick O'Connor   +4 more
wiley   +1 more source

Parvalbumin interneuron deficits in schizophrenia

open access: yesEuropean Neuropsychopharmacology
Parvalbumin-expressing (PV+) interneurons represent one of the most abundant subclasses of cortical interneurons. Owing to their specific electrophysiological and synaptic properties, PV+ interneurons are essential for gating and pacing the activity of excitatory neurons.
openaire   +2 more sources

IgE-Mediated and Non-IgE-Mediated Fish Allergy in Pediatric Age: A Holistic Approach-A Consensus by Diagnostic Commission of the Italian Society of Pediatric Allergy and Immunology. [PDF]

open access: yesMedicina (Kaunas), 2023
Mastrorilli C   +14 more
europepmc   +1 more source

IgE-binding epitopes of various fish parvalbumins exist in a stereoscopic conformation maintained by Ca2+ binding

open access: yesAllergology International, 2016
Ayako Kobayashi   +3 more
doaj   +1 more source

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