Results 161 to 170 of about 6,824 (230)

Poly(ADP-ribose) polymerase (PARP) inhibitors in cardiovascular, and cerebrovascular diseases: mechanisms, current trends and challenge for clinical translation. [PDF]

PeerJ
Fan J, Song Y.
europepmc   +1 more source

Interaction between Poly(ADP-ribose) polymerase-1 and α-synuclein pathology in Parkinson's disease. [PDF]

Front Neurosci
Zhang P, Li Q, Diao X, Zeng S.
europepmc   +1 more source

PARG inhibition suppresses breast cancer progression and potentiates immunoresponse through MTDH degradation mediated by E3 ligase ITCH-dependent ubiquitination. [PDF]

NPJ Breast Cancer
Wang J, Dong Y, Lun W, Nai M, Shi Y, Geng J, Cai W, Liu J, Li H, Li L.   +9 more
europepmc   +1 more source

Tankyrase1/2 inhibitor XAV-939 reverts EMT and suggests that PARylation partially regulates aerobic activities in human hepatocytes and HepG2 cells

Kristof De Vos, Adamantios V. Mavrogiannis, Justina C. Wolters, Susan Schlenner, Keimpe Wierda, Álvaro Cortés Calabuig, Reena Chinnaraj, Vera Dermesrobian, Yeghig Armoudjian, Maarten Jacquemyn, Nikky Corthout, Dirk Daelemans, Pieter Annaert   +12 more
openalex   +2 more sources

Glioblastoma and PARP inhibitors: the importance of patient selection to maximize therapeutic benefits. A critical review. [PDF]

Front Oncol
Dima G, Di Nunno V, Aprile M, Gatto L, Tosoni A, Argento CM, Margotti M, Bartolini S, Franceschi E.   +8 more
europepmc   +1 more source

Reviewer #2 (Public review): SERBP1 interacts with PARP1 and is present in PARylation-dependent protein complexes regulating splicing, cell division, and ribosome biogenesis

Kira Breunig, Xiufen Lei, Mauro Montalbano, Gabriela DA Guardia, Shiva Ostadrahimi, Victoria Alers, Adam Kosti, Jennifer Chiou, Nicole Klein, Corina Vinarov, Lily Wang, Mujia Li, Weidan Song, W Lee Kraus, David S Libich, Stefano Tiziani, Susan T Weintraub, Pedro AF Galante, Luiz OF Penalva   +18 more
openalex   +1 more source

Targeting m⁶A RNA methylation to sensitize cancer cells to DNA-damaging therapies. [PDF]

Discov Oncol
Cesaro B, Venezia S, Tarullo M, Piscopo F, Fatica A.   +4 more
europepmc   +1 more source

Genetic evidence for PARP1 trapping as a driver of PARP inhibitor efficacy in BRCA mutant cancer cells. [PDF]

Nucleic Acids Res
Ribeiro J, Hansen K, van Beek L, Stubbs C, Frigola J, Talbot S, Bentouati S, Hall J, Wijnhoven PWG, Armenia J, Schimpl M, Forment JV, Albertella MR, O'Connor MJ, Illuzzi G.   +14 more
europepmc   +1 more source

Parylation dependent nuclear export of HMGB1 via exportin 1 contributes to morphine tolerance

Yuexin Liang, Daying Zhang, Dongsheng Le, Li Liu, Fan Yang, Shiyu Sun, Guo-Rong Lai, Chao Zhang, Mai-Lin Zhao, Ping-Sheng Liao, Tong Liu, Bing Wang   +11 more
openalex   +1 more source

Poly(ADP-ribose) glycohydrolase enforces p21 degradation via dePARylation to promote gastric cancer progression. [PDF]

J Clin Invest
Hu Y, Bao Q, Huang Y, Wang Y, Zhao X, Nan J, Meng Y, Deng M, Li Y, Zhuang Z, He H, Zu D, Zhong Y, Zhang C, Wang B, Li R, He Y, Wang Q, Liu M, Tainer JA, Shi Y, Cheng X, Jing J, Ye Z.   +23 more
europepmc   +1 more source