Results 181 to 190 of about 6,824 (230)

Molecular functions of PARylation on the dynamics of DNA replication

Lina-Marie Briu
openalex   +1 more source

The zinc finger domains of PARP-1 are selectively and potently inhibited by the Au(I)-based drugs sodium aurothiomalate and aurothioglucose. [PDF]

FEBS Lett
Bashtanova U, Duer MJ.
europepmc   +1 more source

Role of free radicals in PARP inhibition of cervical carcinogenesis: PARylation of HeLa cells, and inhibition of hPARP-1 enzyme

, 2018
Clifford W Fong
openalex   +1 more source

Targeting MARylation and DePARylation in Cancer Therapy: New Promising Therapeutic Opportunities. [PDF]

Cancers (Basel)
Cabeza-Fernández V, Ríos-Sola FJ, Martín-Oliva D, Borrego-Pérez J, Oliver FJ, YéLamos J, Rodríguez-Vargas JM.   +6 more
europepmc   +1 more source

ME-Class2 reveals context dependent regulatory roles for 5-hydroxymethylcytosine [PDF]

, 2019
Edwards, John R, Gabel, Harrison W, Schlosberg, Christopher E, Wu, Dennis Y   +3 more
core   +1 more source

FET proteins and PARylation-dependent condensates promote replication fork reversal and genome stability

Celeste Giansanti, Jack C. Schultz, Jessica Jackson, Alessandro Vindigni, David Cortez   +4 more
openalex   +1 more source

Non-Classical H1-like PARP1 Binding to Chromatosome. [PDF]

Cells
Koshkina D, Maluchenko N, Nilov D, Lyubitelev A, Korovina A, Pushkarev S, Armeev G, Kirpichnikov M, Studitsky V, Feofanov A.   +9 more
europepmc   +1 more source

Oxidative stress triggers RNAPII arrest through PARylation and DNA damage

Thomas QA, Wu L, Lesage E, Iversen HKM, López Martínez D, Kompocholi S, Liu H, Nieto Moreno N, Gregersen LH.   +8 more
europepmc   +1 more source

USP10 deubiquitinase: Physiological function, diseases and therapeutic target (Review). [PDF]

Int J Mol Med
Zhang L, Sun H, Wang Z, Wang Z, Mu Q, Liu Y.   +5 more
europepmc   +1 more source

Defective DNA Damage Response Is a Targetable Therapeutic Vulnerability in ESR1-Mutant Breast Cancer. [PDF]

Cancer Res
Herzog SK, Stevens JH, Gu G, Grimm SL, Cardoza K, Hawkins AGM, Lin H, Ramos D, Beyer AR, Edwards DG, Dustin D, Yang HJ, Liang N, Khan AF, Bawa-Khalfe T, McGrail DJ, Lin SY, Coarfa C, Fuqua SAW.   +18 more
europepmc   +1 more source