Results 111 to 120 of about 5,546 (214)

The treatment with pasireotide in Cushing’s disease: effect of long-term treatment on clinical picture and metabolic profile and management of adverse events in the experience of a single center [PDF]

open access: hybrid, 2019
Chiara Simeoli   +10 more
openalex   +1 more source

Clinical use of pasireotide for Cushing's disease in adults

open access: yesTherapeutics and Clinical Risk Management, 2015
Filippo Ceccato, Carla Scaroni, Marco Boscaro Endocrinology Unit, Department of Medicine, Padova University Hospital, Padova, Italy Cushing’s disease: Excessive corticotroph hormone levels sustained by an adrenocorticotropic hormone-secreting ...
Ceccato F, Scaroni C, Boscaro M
doaj  

AIP and MEN1 mutations and AIP immunohistochemistry in pituitary adenomas in a tertiary referral center. [PDF]

open access: yes, 2019
Background: Pituitary adenomas have a high disease burden due to tumor growth/ invasion and disordered hormonal secretion. Germline mutations in genes such as MEN1 and AIP are associated with early onset of aggressive pituitary adenomas that can be ...
Cano González, David A.   +2 more
core  

Rationale and design of the PAMSARC (pasireotide as maintenance treatment with monthly deep intramuscular injection in SSTR2/3/5-expressing synovial sarcoma and desmoplastic small round cell tumor) multicenter phase 2 trial

open access: yesCancer Treatment and Research Communications
Background: Desmoplastic small round cell tumor (DSRCT) and synovial sarcoma (SySa) are rare cancers primarily affecting adolescents and young adults. Prognosis is generally poor, particularly upon metastasis, due to limited efficacy of chemotherapies ...
Christoph E. Heilig   +19 more
doaj   +1 more source

Basic and Clinical Aspects of the Medical Treatment of Cushings Disease [PDF]

open access: yes, 2013
Under physiological conditions, the production of cortisol is tightly regulated by the so-called hypothalamuspituitary- adrenal (HPA) axis (Figure 1a). Adrenocorticotropin (ACTH) producing cells in the anterior pituitary lobe respond to the hypothalamic ...
Pas, R. (Rob) van der
core  

Insulin-like growth factor-I inhibition with pasireotide decreases cell proliferation and increases apoptosis in pre-malignant lesions of the breast: a phase 1 proof of principle trial [PDF]

open access: gold, 2014
Baljit Singh   +12 more
openalex   +1 more source

Burden of diabetes mellitus in patients with acromegaly treated with second-line pharmacotherapy in Spain

open access: yesClinicoEconomics and Outcomes Research, 2019
Laura Sánchez-Cenizo,1 Javier Aller,2 José Manuel Martínez-Sesmero,3 Nuria Mir,1 Carmen Peral,1 Darío Rubio-Rodríguez,4 Carlos Rubio-Terrés41Medical Department, Pfizer, S.L.U, Madrid, Spain; 2Endocronology ...
Sánchez-Cenizo L   +6 more
doaj  

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