The treatment with pasireotide in Cushing’s disease: effect of long-term treatment on clinical picture and metabolic profile and management of adverse events in the experience of a single center [PDF]
Chiara Simeoli +10 more
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Biochemical control and clinical improvement is induced by long-term pasireotide administration in the majority of patients with Cushing[apos]s disease persistent after pituitary surgery [PDF]
Erika Messina +4 more
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A single-surgeon series of 93 patients undergoing pancreatectomy with pasireotide for prevention of pancreatic fistula [PDF]
C.B. Polen +4 more
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Clinical use of pasireotide for Cushing's disease in adults
Filippo Ceccato, Carla Scaroni, Marco Boscaro Endocrinology Unit, Department of Medicine, Padova University Hospital, Padova, Italy Cushing’s disease: Excessive corticotroph hormone levels sustained by an adrenocorticotropic hormone-secreting ...
Ceccato F, Scaroni C, Boscaro M
doaj
AIP and MEN1 mutations and AIP immunohistochemistry in pituitary adenomas in a tertiary referral center. [PDF]
Background: Pituitary adenomas have a high disease burden due to tumor growth/ invasion and disordered hormonal secretion. Germline mutations in genes such as MEN1 and AIP are associated with early onset of aggressive pituitary adenomas that can be ...
Cano González, David A. +2 more
core
Background: Desmoplastic small round cell tumor (DSRCT) and synovial sarcoma (SySa) are rare cancers primarily affecting adolescents and young adults. Prognosis is generally poor, particularly upon metastasis, due to limited efficacy of chemotherapies ...
Christoph E. Heilig +19 more
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Basic and Clinical Aspects of the Medical Treatment of Cushings Disease [PDF]
Under physiological conditions, the production of cortisol is tightly regulated by the so-called hypothalamuspituitary- adrenal (HPA) axis (Figure 1a). Adrenocorticotropin (ACTH) producing cells in the anterior pituitary lobe respond to the hypothalamic ...
Pas, R. (Rob) van der
core
Insulin-like growth factor-I inhibition with pasireotide decreases cell proliferation and increases apoptosis in pre-malignant lesions of the breast: a phase 1 proof of principle trial [PDF]
Baljit Singh +12 more
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Laura Sánchez-Cenizo,1 Javier Aller,2 José Manuel Martínez-Sesmero,3 Nuria Mir,1 Carmen Peral,1 Darío Rubio-Rodríguez,4 Carlos Rubio-Terrés41Medical Department, Pfizer, S.L.U, Madrid, Spain; 2Endocronology ...
Sánchez-Cenizo L +6 more
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