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Prevalence, comorbidities and treatment outcomes of patients with Acromegaly in Qatar. Running title: Acromegaly in Qatar

Elhadd T, Mahmuod EAA, Ponirakis G, Dabbous Z, Rohani Z, Abdalrubb A, Malik RA, Bashir M.   +7 more
europepmc   +1 more source

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Pasireotide - potential treatment option for McCune Albright-associated acromegaly.

European Journal of Endocrinology, 2023
Only 30% of patients with McCune Albright syndrome (MAS)-associated acromegaly achieve biochemical control under first-generation somatostatin receptor ligands (fg-SRLs), while pegvisomant fails to normalize IGF-I in >20% of cases.
M. Ilie, G. Raverot, Aude Brac de la Perrière   +2 more
semanticscholar   +1 more source

Case Report: Opposite Tumoral and Hormonal Responses to Low-dose Pasireotide in Cushing's Disease.

Endocrine, Metabolic & Immune Disorders - Drug Targets, 2023
BACKGROUND Pasireotide is a multireceptor somatostatin analogue approved for the treatment of patients with Cushing's disease (CD) who are ineligible or poor candidates for pituitary surgery.
A. L. Serban, B. Zampetti, Andrea Saladino, V. Favero, I. Chiodini, R. Cozzi   +5 more
semanticscholar   +1 more source

The Role of the GH Receptor Polymorphisms as a Prognostic Factor of Vertebral Fractures in Acromegalic Patients Resistant to First-generation SSAs and Treated with Pegvisomant or Pasireotide LAR.

Endocrine, Metabolic & Immune Disorders - Drug Targets
BACKGROUND Acromegaly is associated with skeletal fragility and increased prevalence of vertebral fractures (VF). Two isoforms of GH receptor (GHR) have been described, which differ in the presence or absence of a transcript of exon 3 of the GHR gene ...
F. Costanza, S. Chiloiro, A. Giampietro, Flavia Angelini, A. Infante, A. Pontecorvi, L. De Marinis, Antonio Bianchi   +7 more
semanticscholar   +1 more source

SAT-052 EFFICACY AND LONG-TERM SAFETY OF PASIREOTIDE TREATMENT IN PATIENTS WITH ACROMEGALY, BETWEEN 2018 TO 2023. IMBANACO CLINIC CALI -COLOMBIA:

Journal of the Endocrine Society
A. Abreu Lomba: None. S.D. Riveros Bermudez: None. D.A. Vernaza Trujillo: None. Methodology: A descriptive, retrospective cohort study was conducted to evaluate the effectiveness and glycemic behavior of Pasireotide treatment in adults diagnosed with ...
A. Lomba, Sonia Dayana Riveros Bermudez, David Alexander Vernaza Trujillo   +2 more
semanticscholar   +1 more source