Results 81 to 90 of about 5,546 (214)

A Five‐Year Journey to Diagnosis: Resolving Persistent Hypoglycemia Through Successful Insulinoma Resection—A Case Report

open access: yesClinical Case Reports, Volume 13, Issue 3, March 2025.
ABSTRACT Insulinoma is a rare functional pancreatic neuroendocrine tumor with an annual prevalence of 0.5–5 cases per million. It is characterized by excessive insulin secretion, leading to recurrent hypoglycemia, often diagnosed through Whipple's triad: hypoglycemic symptoms, documented low plasma glucose, and symptom resolution after glucose ...
Ankit Shrestha   +6 more
wiley   +1 more source

Chromogranin A: From Laboratory to Clinical Aspects of Patients with Neuroendocrine Tumors [PDF]

open access: yes, 2018
Background. Neuroendocrine tumors (NETs) are characterized by having behavior and prognosis that depend upon tumor histology, primary site, staging, and proliferative index.
Baldelli, Roberto   +8 more
core   +1 more source

Managing Hypoglycaemia in Patients With Insulinoma—A Tertiary Centre Experience and Review of the Literature

open access: yesClinical Endocrinology, Volume 102, Issue 3, Page 344-354, March 2025.
ABSTRACT The management of hypoglycaemia is pivotal in the care of patients with insulinoma. Blood glucose monitoring and regulation needs careful attention pre‐ and peri‐operatively for patients undergoing surgical resection and as part of the long‐term management for patients with inoperable or metastatic disease.
Sophie Howarth   +3 more
wiley   +1 more source

Pasireotide-LAR in acromegaly patients treated with a combination therapy: a real-life study

open access: yesEndocrine Connections, 2019
Purpose: Little data are available regarding the safety and efficacy of s witching to Pasireotide-LAR monotherapy in acromegaly patients with partial resistance to first-generation somatostatin agonists (1gSRL) who require combination treatment with ...
Hélène Lasolle   +5 more
doaj   +1 more source

Grading and staging for pituitary neuroendocrine tumors

open access: yesBrain Pathology, Volume 35, Issue 1, January 2025.
Abstract Pituitary adenoma/pituitary neuroendocrine tumors (PitNETs) are the second most common primary intracranial tumor and the most frequent neuroendocrine tumors/neoplasms of the human body. Thus, they are one of the most frequent diagnoses in neuropathologist's practise.
Chiara Villa   +6 more
wiley   +1 more source

New cross-roads for second line medical therapy in acromegaly [PDF]

open access: yesArchives of the Balkan Medical Union, 2018
Acromegaly is a complex disorder caused by growth hormone excess mostly due to a pituitary adenoma. Surgery represents the first option but rate of long time success is almost 50% thus the patients need other therapies.
Adina Ghemigian   +5 more
doaj  

Successful Control of Hypoglycemia with Pasireotide LAR in a Patient with Inappropriate Insulin Secretion

open access: yesClinical Pharmacology: Advances and Applications, 2021
Alexia Rouland,1 Benjamin Bouillet,1,2 Pauline Legris,1 Isabelle Simoneau,2 Jean-Michel Petit,1,2 Bruno Vergès1,2 1Endocrinology Diabetics and Metabolic Disorders Department, Dijon University Hospital, Dijon, France; 2French National Health and ...
Rouland A   +5 more
doaj  

Efficacy of combined treatment with pasireotide, pegvisomant and cabergoline in an acromegalic patient resistant to other treatments: a case report

open access: yesBMC Endocrine Disorders, 2018
Background The approach to acromegalic patients with persistent acromegaly after surgery and inadequate response to first-generation somatostatin receptor ligands (SRLs) should be strictly tailored.
A. Ciresi   +3 more
doaj   +1 more source

Somatostatin receptors in pituitary somatotroph adenomas as predictors of response to somatostatin receptor ligands: A pathologist's perspective

open access: yesBrain Pathology, Volume 35, Issue 1, January 2025.
This article reviews the major biological characteristics of somatostatin receptors (SST2 and SST5) in anterior pituitary tumors, and the immunohistochemical evaluation of their expression as predictors of response to pharmacological therapy with SST ligands.
Laura Botelho   +5 more
wiley   +1 more source

A szomatosztatinanalógok hatékonysága a neuroendokrin daganatok kezelésében az új klinikai vizsgálatok tükrében [PDF]

open access: yes, 2015
Due to their inhibitory effects on hormone secretion, somatostatin analogues are of pivotal importance in the symptomatic treatment of hormone-secreting neuroendocrine tumours.
Igaz, Péter
core   +1 more source

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