Results 161 to 170 of about 316,944 (217)

Adolescent Cannabis Use After Cannabis Legalization and the COVID-19 Pandemic.

JAMA Netw Open
Young-Wolff KC, Slama NE, Pacula RL, Padon AA, Silver LD, Sterling SA, Satre DD, Campbell CI, Does MB, Alexeeff SE.   +9 more
europepmc   +1 more source

Screening of Low-Tumorigenic MDCK Cells for Potential Influenza Vaccine Substrates and Transcriptomic Analyses. [PDF]

Int J Mol Sci
Zhou L, Li X, Chen J, Liu Y, Zhang Y, Gong X, Meng Q, Li Z.   +7 more
europepmc   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Modeling age-related methylation changes in vitro with intestinal organoids. [PDF]

BMC Biol
Vaidya H, Calendo G, Keith K, Pompetti A, Balch C, Madzo J, Jelinek J, Issa JJ.   +7 more
europepmc   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

The P protein T25M substitution is involved in the quasispecies and virulence of Newcastle disease virus. [PDF]

Microbiol Spectr
Daguia-Wenam P-T, Lu K, Zhou X, Yan C, Tong L, Liu H, Yang Z.   +6 more
europepmc   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Effects of Sodium Monensin and a Tannin-Yeast Blend on Intake, Milk Yield, and Methane Emissions in Lactating Holstein Cows. [PDF]

Animals (Basel)
Piuzana LG, Tomich TR, Rotta PP, Carvalho D, Amorim WPF, Silva LHR, Vieira JVF, Ribeiro EF, Silva ALD.   +8 more
europepmc   +1 more source

Small molecules promote the in vitro expansion and passaging of adult mouse pancreatic islets. [PDF]

Biochem Biophys Rep
Zhang L, Liu K, Zhang X, Cui Y, Hu H, Hu X.   +5 more
europepmc   +1 more source

What triggers seismicity thousands of kilometers away from a mainshock? [PDF]

Sci Adv
Huang C, Yang J.
europepmc   +1 more source