Results 111 to 120 of about 1,240,534 (281)
Passage of the Comprehensive Immunosuppressive Drug Coverage for Kidney Transplant Patients Act—a Chance to Celebrate and Reflect [PDF]
Journal of the American Society of Nephrology, 2021 John S. Gill +2 more
openaire +2 more sources
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Non market valuation in New Zealand: 1974 through 2005 [PDF]
, 2007 Non-market valuation (NMV) is recognized as an essential tool in policy decision making worldwide. In this paper, we investigate the history of NMV, specifically in relation to New Zealand (NZ), by compiling and analyzing all available published studies.
Kaval, Pamela, Yao, Richard
core +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Determinants of Labor Market Outcomes of Disabled Men Before and After the Americans with Disabilities Act of 1990 [PDF]
The study compares the labor market experience of men with disabilities before and after the Americans with Disabilities Act of 1990. The handful of studies that have focused on the wage impact of disabilities have either not fully incorporated the ...
Choe, Chung
core
George S. Schuyler, Black and Conservative [PDF]
, 2009 When George S. Schuyler published his autobiography Black and Conservative in 1966, its title was intended to be paradoxical, underscoring how the two adjectives were rarely used together, particularly in an era that had recently seen the passage of the ...
Lock, Helen
core +1 more source
Documenting Successes 30 Years After Passage of the Ryan White CARE Act
Journal of the Association of Nurses in AIDS Care, 2021 John, Weiser +3 more
openaire +3 more sources
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source