Results 151 to 160 of about 11,487 (192)

New oxacycles on the block: benzodioxepinones via a Passerini reaction

Molecular Diversity, 2022
Oxacycles and benzoxepanes are privileged motifs present in a variety of natural products and functional molecules. However, their synthetic access is limited. Here, we demonstrate a rapid synthesis of unprecedented benzoxepanes from readily available starting materials in one step via a Passerini multicomponent reaction. The reaction proceeds smoothly
Michael Fragkiadakis, Marios Zingiridis, Edward Loukopoulos, Constantinos G. Neochoritis   +3 more
openaire   +2 more sources

Introducing Multicomponent Reactions to Polymer Science: Passerini Reactions of Renewable Monomers

Journal of the American Chemical Society, 2011
Combination of the Passerini three component-reaction (3CR) and olefin metathesis led to the formation of poly[1-(alkyl carbamoyl)alkyl alkanoates], a new class of polyesters with amide moieties in their side chain, from renewable resources. Two different approaches were studied and compared to each other.
Kreye, O., Tóth, T., Meier, M. A. R.
openaire   +4 more sources

ChemInform Abstract: Regioselective Passerini and Passerini—Knoevenagel Reactions with vic‐Diketo Amides.

ChemInform, 2014
AbstractVicinal diketo amides react with isonitriles and carboxylic acids to α‐acyloxy β‐keto carboxamides.
Jan Rossbach, Klaus Harms, Ulrich Koert
openaire   +1 more source

Regioselective Passerini and Passerini–Knoevenagel Reactions with vic‐Diketo Amides

European Journal of Organic Chemistry, 2013
AbstractThe Passerini reaction of vic‐diketo amides with a variety of isocyanides and carboxylic acids has been examined. α‐Acyloxy β‐keto carboxamides were formed regioselectively as the major products. For the Passerini reactions with electron‐withdrawing‐group‐substituted acetic acids, a one‐pot Passerini–Knoevenagel reaction was accomplished by the
Jan Roßbach, Klaus Harms, Ulrich Koert
openaire   +1 more source

Still Unconquered: Enantioselective Passerini and Ugi Multicomponent Reactions

Accounts of Chemical Research, 2018
The Passerini three-component (P-3CR) and the Ugi four-component (U-4CR) are two of the most prominent isocyanide-based multicomponent reactions (IMCRs). The P-3CR transforms isocyanides, aldehydes (ketones), and carboxylic acids to α-acyloxy carboxamides, while the U-4CR converts isocyanides, aldehydes (ketones), amines, and carboxylic acids to α ...
Qian Wang, De-Xian Wang, Mei-Xiang Wang, Jieping Zhu   +3 more
openaire   +2 more sources

FormylBODIPYs: Privileged Building Blocks for Multicomponent Reactions. The Case of the Passerini Reaction

The Journal of Organic Chemistry, 2016
Eleven formyl-containing BODIPY dyes were prepared by means of either the Liebeskind-Srogl cross-coupling reaction or the Vilsmeier reaction. These dyes were used as components in the Passerini reaction to give highly substituted BODIPY dyes. A joined spectroscopic and theoretical characterization of the synthesized compounds was conducted to unravel ...
Diana E, Ramírez-Ornelas, Enrique, Alvarado-Martínez, Jorge, Bañuelos, Iñigo, López Arbeloa, Teresa, Arbeloa, Héctor M, Mora-Montes, Luis A, Pérez-García, Eduardo, Peña-Cabrera   +7 more
openaire   +2 more sources

Enhanced reactivity of dendrons in the Passerini three-component reaction

Chemical Communications, 2015
An unexpected substituent effect that accelerates Passerini reactions in THF has enabled the synthesis of three generations of dendrimers.
Jo-Ann, Jee, Shuang, Song, Jonathan G, Rudick   +2 more
openaire   +2 more sources

Phosphoric Acid-Catalyzed Asymmetric Classic Passerini Reaction

Journal of the American Chemical Society, 2015
An efficient enantioselective classic three-component Passerini reaction with a broad substrate scope in the presence of a chiral phosphoric acid catalyst has been developed. This represents the general example for classic three-component Passerini reaction with good to excellent enantioselectivies involving aromatic aldehydes and the bulky ...
Jian, Zhang, Shao-Xia, Lin, Dao-Juan, Cheng, Xin-Yuan, Liu, Bin, Tan   +4 more
openaire   +2 more sources

Nonorganometallic pathway of the Passerini reaction assisted by titanium tetrachloride

Organometallics, 1993
The Passerini reaction assisted by TiCl4 is a three component reaction (RNC, R'2CO, TiCl4) leading to C-C bond formation between the carbonyl and the isonitrile groups, and the formation of alpha-hydroxy amides. In order to clarify the mechanism of the reaction, we have isolated TiCl4-RNC and TiCl4-R2CO adducts, {2,6-Me2C6H3NC)TiCl3]2(mu-Cl)2}2, 2 ...
CAROFIGLIO, TOMMASO, P. G. COZZI, C. FLORIANI, A. CHIESIVILLA, C. RIZZOLI   +4 more
openaire   +2 more sources

Passerini reaction: Synthesis and applications in polymer chemistry

European Polymer Journal, 2023
Aditi Arora, Brajendra K Singh
exaly