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Revisiting the Passerini Reaction under Eco-Friendly Reaction Conditions

Synlett, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Carlos Kleber Z Andrade   +1 more
exaly   +2 more sources

Synthesis of d-glycopyranosyl depsipeptides using Passerini reaction

Carbohydrate Research, 2021
A protocol based on Passerini multi-component reaction has been developed for facile, efficient and atom economical synthesis of a small library of twenty potential bioactive (2R)-2-(d-glycopyranosyl)-2-acyloxyacetamides using perbenzylated d-glycopyranosyl aldehydes, substituted isocyanides and different aliphatic/aromatic carboxylic acids. All twenty
Bhawani Shankar, Ashok K Prasad
exaly   +3 more sources

A direct link between the Passerini reaction and α-lactams

Tetrahedron, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
István Lengyel   +2 more
exaly   +2 more sources

The Passerini Reaction

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
BANFI, LUCA, RIVA, RENATA
openaire   +2 more sources

Solvent‐Free Passerini Reactions

Synthetic Communications, 2008
The influence of the substrate structure and concentration on the yield of the Passerini reaction was studied. A new, solvent-free methodology for a convenient preparation of alpha-acyloxyamides 4 was established and compared to the classical methodology. A higher reaction yield was obtained in shorter time, especially in the case of aromatic aldehydes.
Koszelewski, Dominik   +3 more
openaire   +1 more source

Synthesis of Glycomimetics by Diastereoselective Passerini Reaction

The Journal of Organic Chemistry, 2018
We describe the utilization of bis-isopropylidene-protected d-fructose-derived aldehyde in the Passerini reaction with various acids and isocyanides. A library of densely functionalized glycomimetics bearing up to 3 carbohydrate units was obtained in high yields and diastereoselectivities.
Kristina Vlahoviček-Kahlina   +4 more
openaire   +3 more sources

Synthetic Applications of Passerini Reaction

Current Organic Chemistry, 2012
Passerini reaction involving an oxo component, an isocyanide, and a nucleophile in a single step to prepare -acyloxy carbox- amide, was first discovered by Passerini about 90 years ago. Various modifications of this reaction have already been developed such as Lewis acids catalysis, in situ oxidation of alcohols to aldehydes, in situ oxidation of ...
Ali Reza Kazemizadeh, Ali Ramazani
openaire   +1 more source

Catalytic Enantioselective Passerini Three‐Component Reaction

Angewandte Chemie International Edition, 2007
A [(salen)-AlIIICl] complex catalyzes the Passerini three-component reaction of an aldehyde, a carboxylic acid, and an isocyanide to afford alpha -acyloxyamides, e.g., I, with good to excellent enantioselectivity. A variety of nonchelating substrates can be used to generate the versatile chiral products. [on SciFinder (R)]
Wang, Shi-Xin   +3 more
openaire   +2 more sources

Homologation of Ugi and Passerini reactions using ynamides

Drug Discovery Today: Technologies, 2018
Being important biological and pharmacological units, β-amino amides and β-acyloxy amides have a privileged position in both academia and industry. Developing a methods to prepare them has gained attention. Ynamides, which possess dual nucleophilic and electrophilic properties, are similar to isonitriles. In this review, usage of ynamides in the single
Bo, Huang, Sunliang, Cui
openaire   +2 more sources

An intramolecular passerini reaction: Synthesis of hydrastine.

Tetrahedron Letters, 1981
Abstract An intramolecular Passerini reaction between 3,4-methylenedioxyphenethylisocyanide and opianic acid is applied in a total synthesis of hydrastine, a phthalideisoquinoline alkaloid.
J.R. Falck, Sukumar Manna
openaire   +1 more source

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