Results 141 to 150 of about 7,368,504 (211)
Potentially prebiotic isocyanide activation chemistry drives RNA assembly.
Zhang SJ, Jia X, DasGupta S, Szostak JW.
europepmc +1 more source
Phosphoric acid-catalyzed asymmetric classic Passerini reaction.
An efficient enantioselective classic three-component Passerini reaction with a broad substrate scope in the presence of a chiral phosphoric acid catalyst has been developed. This represents the general example for classic three-component Passerini reaction with good to excellent enantioselectivies involving aromatic aldehydes and the bulky ...
Jian Zhang +4 more
semanticscholar +5 more sources
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Synthesis of d-glycopyranosyl depsipeptides using Passerini reaction.
Carbohydrate Research, 2021A protocol based on Passerini multi-component reaction has been developed for facile, efficient and atom economical synthesis of a small library of twenty potential bioactive (2R)-2-(d-glycopyranosyl)-2-acyloxyacetamides using perbenzylated d ...
B. Kumar +5 more
semanticscholar +3 more sources
On-Resin Passerini Reaction toward C-Terminal Photocaged Peptides.
An on-resin, three-component Passerini reaction was developed to synthesize C-terminal photocaged peptides. Highly compatible with conventional Fmoc SPPS, this reaction produces peptides with a C-terminal o-amido-6-nitroveratryl (αANV) ester in one pot ...
Wing-Ho So, Jiang Xia
semanticscholar +3 more sources
Journal of Organic Chemistry, 2023
α-Acyloxy carboxamides are important multifunctional natural products that show bioactive and pharmacological activities. Traditional three-component Passerini reactions among isocyanates, aldehydes/ketones, and carboxylic acids for affording α-acyloxy ...
Yi-Kang Wu +4 more
semanticscholar +1 more source
α-Acyloxy carboxamides are important multifunctional natural products that show bioactive and pharmacological activities. Traditional three-component Passerini reactions among isocyanates, aldehydes/ketones, and carboxylic acids for affording α-acyloxy ...
Yi-Kang Wu +4 more
semanticscholar +1 more source
New oxacycles on the block: benzodioxepinones via a Passerini reaction
Molecular Diversity, 2022Oxacycles and benzoxepanes are privileged motifs present in a variety of natural products and functional molecules. However, their synthetic access is limited. Here, we demonstrate a rapid synthesis of unprecedented benzoxepanes from readily available starting materials in one step via a Passerini multicomponent reaction. The reaction proceeds smoothly
Michael Fragkiadakis +3 more
semanticscholar +3 more sources
Drug Discovery for Soft Drugs on TRPV1 and TRPM8 Channels Using the Passerini Reaction.
Multicomponent transformations, such as Ugi and Passerini reactions, allow for the fast synthesis of libraries of medium complexity, avoiding the formation of waste residues and significantly reducing time and money expenditure. Although the Ugi reaction
T. Pirali +5 more
semanticscholar +2 more sources
Enediyne-Comprising Amino Aldehydes in the Passerini Reaction
Multicomponent reactions represent a highly efficient approach to a broad spectrum of structurally diverse compounds starting from simple and affordable compounds. A focused library of tweezers-like compounds is prepared by employing the multicomponent Passerini reaction comprising enediyne-derived amino aldehydes.
Ivanka Jeric, Matija Gredičak
exaly +3 more sources
ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
BANFI, LUCA, RIVA, RENATA
openaire +2 more sources
AbstractFor Abstract see ChemInform Abstract in Full Text.
BANFI, LUCA, RIVA, RENATA
openaire +2 more sources

