Results 101 to 110 of about 41,637 (195)

Senescent Cell Derived Artificial Vesicle‐Based Senolytic Sonovaccine Platform with Augmented Lymph Node Delivery and Antigen Cross‐Presentation Efficacy

open access: yesAdvanced Science, Volume 13, Issue 46, 17 August 2026.
A senolytic sonovaccine platform (SenoVac) is developed, in which senescent cell‐derived vesicles serve as broad senescent cell antigen reservior. The “2‐step” click chemistry strategy for effective lymph node delivery, and ultrasound‐triggered endosomal escape to boost cross‐presentation, ensures efficient senescent cell clearance and disease ...
Liang Zhang   +10 more
wiley   +1 more source

Long‐term safety and immunogenicity of ABvac40 active immunotherapy in mild cognitive impairment and very mild Alzheimer's disease: Results from AB1601 phase 2 extension study

open access: yesAlzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION ABvac40 is an active immunotherapy targeting Aβ40, the main component of cerebrovascular deposition in Alzheimer's disease (AD). A 24‐month randomized, placebo‐controlled phase 2 study (Part A) showed favorable safety and robust immunogenicity, with exploratory signals of clinical efficacy.
María Pascual‐Lucas   +15 more
wiley   +1 more source

Passive Immunization with a Single Monoclonal Neutralizing Antibody Protects against Cutaneous and Mucosal Mouse Papillomavirus Infections. [PDF]

open access: yesJ Virol, 2022
Brendle SA   +14 more
europepmc   +1 more source

Clinically Diagnosed Decompensated Chronic Liver Disease With Suspected Portal Hypertension in a One‐Year‐Old Infant: Diagnostic Challenges in a Resource‐Limited Setting

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Chronic liver disease in infancy is uncommon, diagnostically demanding, and rarely reported from sub‐Saharan Africa, where advanced hepatologic evaluation is seldom accessible. We describe a one‐year‐old boy from rural Somaliland who presented with a two‐week history of progressive abdominal distension, followed by jaundice, hematemesis and ...
Khadar Jama Ibrahim   +3 more
wiley   +1 more source

Therapeutic efficacy of combined active and passive immunization in ART-suppressed, SHIV-infected rhesus macaques. [PDF]

open access: yesNat Commun, 2022
Walker-Sperling VEK   +19 more
europepmc   +1 more source

A Systematic Review on Disease‐Modifying Therapies in Parkinsonian Disorders

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 357-374, August 2026.
Parkinsonian disorders, including Parkinson's disease, Lewy body dementia, multiple system atrophy, and progressive supranuclear palsy, are progressive neurodegenerative conditions with no treatment options to slow disease progression. This systematic review provides an overview of evidence of disease‐modifying therapies that have been evaluated in ...
Pepijn P.N.M. Eijsvogel   +3 more
wiley   +1 more source

COVID-19 mRNA vaccine in pregnancy and newborn passive immunization: a case report. [PDF]

open access: yesFuture Sci OA, 2022
Kassis NE   +5 more
europepmc   +1 more source

Active Vaccination Strategies for Alzheimer's Disease: An Expanded Review

open access: yesEuropean Journal of Immunology, Volume 56, Issue 8, August 2026.
Overview of immunotherapeutic strategies targeting Alzheimer's disease (AD) pathology and their clinical implications. (Left) Key neuropathological hallmarks of AD, including extracellular amyloid‐beta (Aβ) aggregates and intraneuronal hyperphosphorylated Tau (phospho‐Tau), converge to produce synaptic failure, neuroinflammation and neuronal ...
Antonella Comitato   +2 more
wiley   +1 more source

Passive Immunization of Anti bZP3 (Zone Pellucida3) in Wistar Rat (Rattus novergicus) and Mouse (Mus musculus)

open access: yesMedia Peternakan, 2012
This study was aimed at comparing the influence of anti bZP3’s passive immunization on anti-anti bZP3’s titer and pregnancy level on Wistar rats and mice. This study employed factorial design experiment with completely randomized design. The first factor
Y. Pantiwati
doaj  

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