Results 81 to 90 of about 1,115,146 (219)

Passive immunity to porcine epidemic diarrhea virus following immunization of pregnant gilts with a recombinant orf virus vector expressing the spike protein

Archives of Virology, 2018
Passive immunity is critical for protection of neonatal piglets against porcine epidemic diarrhea virus (PEDV). Here, we investigated the immunogenicity of an orf virus (ORFV) vector expressing the full-length spike (S) protein of PEDV (ORFV-PEDV-S) in ...
Lok Raj Joshi, Faten A. Okda, Aaron Singrey, M. F. Maggioli, T. Faccin, M. H. Fernandes, Kyle S. Hain, S. Dee, F. V. Bauermann, E. Nelson, D. Diel   +10 more
semanticscholar   +1 more source

A Case for Anti‐IgE Vaccination

Allergy, EarlyView.
ABSTRACT Immunoglobulin E (IgE) plays a central role in allergic diseases by binding to the high‐affinity receptor FcεRI on mast cells and basophils, where allergen‐induced crosslinking triggers potent inflammatory responses. Various mechanisms by which IgE responses are generated and functionally regulated remain elusive despite many years of research.
Paul Engeroff, Zahra Gharailoo, Monique Vogel, Martin F. Bachmann   +3 more
wiley   +1 more source

Real-world data and clinical management experience in passive immunization for respiratory syncytial virus prevention in children

Vaccine: X
Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infections in children under 5 years of age worldwide. Currently, there are no approved curative treatments, and clinical management remains primarily focused on ...
Yongping Xie, Xin Cong, Yan Li, Lisu Huang   +3 more
doaj   +1 more source

Passive Immunization with Tau Oligomer Monoclonal Antibody Reverses Tauopathy Phenotypes without Affecting Hyperphosphorylated Neurofibrillary Tangles

Journal of Neuroscience, 2014
Recent findings suggest that tau oligomers, which form before neurofibrillary tangles (NFTs), are the true neurotoxic tau entities in neurodegenerative tauopathies, including Alzheimer's disease (AD).
D. Castillo-Carranza, U. Sengupta, Marcos J. Guerrero-Muñoz, C. Lasagna-Reeves, J. Gerson, Gurpreet Singh, D. Estes, A. Barrett, K. Dineley, G. Jackson, R. Kayed   +10 more
semanticscholar   +1 more source

Swedish Infants Developed Pertussis at a Younger Age if Their Mother Was the Possible Source of Infection in 2009–2015

Acta Paediatrica, EarlyView.
ABSTRACT Aim The aim of this study was to investigate the possible source of laboratory‐confirmed pertussis in infants under 6 months of age. Methods This nationwide prospective study was based on laboratory‐confirmed cases reported in the enhanced pertussis surveillance in Sweden from 2009 to 2015. The parents or carers of 345 infants were interviewed
Bernice Aronsson, Lennart Nilsson, Jann Storsaeter, Henrik Källberg, Emma Appelqvist   +4 more
wiley   +1 more source

Ethical Considerations Regarding the Vaccination of Children—The Power Dynamics Between Doctors and Parents

Acta Paediatrica, EarlyView.
ABSTRACT While childhood vaccination programmes provide outstanding contributions to improving health, they can also pose challenges through the interactions between parents and healthcare. This paper focuses on the ethical dimensions of interactions between healthcare professionals and parents. Since the knowledge that professionals possess creates an
Mikael Sandlund, Ingemar Engström, Anders Castor   +2 more
wiley   +1 more source

A real-world based study for immunogenicity and safety for three immunization schedules of polio vaccine

Scientific Reports
To evaluate the immunogencity and safety for three immunization schedules of inactivated poliovirus vaccine (IPV) and bivalent oral poliovirus vaccine (bOPV) for providing a basis for further optimization of the polio sequential immunization schedule. To
Li Sun, Shi-fan Wang, Yi-qing Zhu, Ya-fei Wang, Jun-mian Zhang, Jing-hui Wang, Yan-li Cong, Jing Li, Xiao-qin Liu, Sha-sha Han, Yu Guo, Qi Li   +11 more
doaj   +1 more source

Tau‐targeting active immunotherapy slows progression and reduces pathology in mouse models of tauopathy

Brain Pathology, EarlyView.
The efficacy of the novel anti‐tau active immunotherapy, p5555kb, was tested using two mouse models of tau pathology. p5555kb inoculation increased the survival rate and reduced tau pathology in tau‐overexpressing P301L mice and decreased tau seeding in the brains of C57BL/6 mice injected with human‐purified Alzheimer's disease tau.
Christopher M. Brown, Jeanne K. Brooks, Louise Kelly, Madeline M. Vroom, Matthew Longo, Jean‐Cosme Dodart, Roxana Carare, Justin D. Boyd   +7 more
wiley   +1 more source

Passive immunization to reduce Campylobacter jejuni colonization and transmission in broiler chickens

Veterinary Research, 2014
Campylobacter jejuni is the most common cause of bacterium-mediated diarrheal disease in humans worldwide. Poultry products are considered the most important source of C.
D. Hermans, K. van Steendam, E. Verbrugghe, M. Verlinden, A. Martel, Tomasz Seliwiorstow, M. Heyndrickx, F. Haesebrouck, L. De Zutter, D. Deforce, F. Pasmans   +10 more
semanticscholar   +1 more source

Phage Therapy: Targeting the Gut Microbiota for the Treatment of Acute Pancreatitis

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Acute pancreatitis (AP) is a common clinical inflammatory condition whose severity is closely associated with both local pancreatic injury and systemic complications. Research indicates that gut microbiota dysbiosis and subsequent bacterial translocation can exacerbate disease progression via the gut–pancreas axis, representing a critical ...
Jiawei Chen, Caihan Duan, Keyi Zhang, Jun Liu, Chaoqun Han   +4 more
wiley   +1 more source