Results 71 to 80 of about 13,458,883 (414)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

On the future of architecture

open access: yesПроект Байкал
In postavantgarde culture, the future has become an object of desire and obvious value. The uncontested belief that every new thing should be accepted as an undoubted good lies at the heart of numerous utopias and speculations.
Александр Раппапорт
doaj   +1 more source

Does our Past have a Motivational Effect? Our Reasons for Acting: Sartre’s Philosophy of Action

open access: yesEthics in Progress, 2013
The goal of my paper is to consider how one chooses one’s own action. First, I will try to understand how both his past and his environment can condition someone's action.
Yoann Malinge
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Rens Krijgsman: Early Chinese Manuscript Collections: Sayings, Memory, Verse, and Knowledge. Studies in the History of Chinese Texts

open access: yesAsian Studies
The book under review is a study of manuscript texts from Warring States and early imperial China (approximately the 5th to 2nd centuries BCE); its specific topic is “manuscript collections,” that is, “single manuscripts containing multiple (originally)
Newell Ann Van Auken
doaj   +1 more source

Les turbulences du temps : linéarités, cycles et résurgences dans The Death of the Heart d’Elizabeth Bowen

open access: yesÉtudes Britanniques Contemporaines, 2009
Critics have often described The Death of the Heart as a Bildungsroman centred on the character of Portia, in her progress towards maturity. If such a vision is undoubtedly valid, this article attempts to show that the novel can be better comprehended by
Céline Magot
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Real Estate Agent Remarks: Help or Hype? [PDF]

open access: yes
This article groups the remarks of a multiple listing service listing into common themes and then uses a hedonic pricing model to determine whether such comments are priced in a meaningful way.
Jerry T. Haag   +2 more
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

US Real Estate Agent Income and Commercial/Investment Activities [PDF]

open access: yes
This article uses canonical correlation analysis to investigate the income characteristics of active real estate agents in the United States who elected to participate in commercial and investment transactions.
Donald R. Epley
core  

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