Results 101 to 110 of about 1,385,162 (283)
Clinical Validation of Plasma p‐217tau in Neurological Diseases
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi +13 more
wiley +1 more source
The Multifaceted Nature of Macrophages in Cardiovascular Disease
BiomedicinesAs the leading cause of mortality worldwide, cardiovascular disease (CVD) represents a variety of heart diseases and vascular disorders, including atherosclerosis, aneurysm, ischemic injury in the heart and brain, arrythmias, and heart failure ...
Cindy X. Li, Lixia Yue
doaj +1 more source
A Private Sector Perspective on the Celtic Tiger Experience [PDF]
International Relations/Trade,
McArdle, Pat
core +1 more source
Von Economo Neuron Loss in Frontotemporal Dementia: A Meta‐Analysis of Neuropathological Studies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Von Economo neurons (VENs) have been reported to be vulnerable to neurodegeneration in frontotemporal dementia (FTD), particularly the behavioral variant (bvFTD), but these findings have not been systematically assessed across independent brain banks.
Daniel Talmasov +2 more
wiley +1 more source
, 2014 We describe todolists (top-down skiplists), a variant of skiplists (Pugh 1990) that can execute searches using at most $\log_{2-\varepsilon} n + O(1)$ binary comparisons per search and that have amortized update time $O(\varepsilon^{-1}\log n)$.
Barba, Luis, Morin, Pat
core
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Researching mobile learning: January to September 2008 (final report) [PDF]
, 2009 This report brought together the findings from the third phase of a two-year development and research project that focused on the impact of one-to-one personal ownership of mobile devices.
McFarlane, Angela, Triggs, Pat
core
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
A knowledge-based system for monitoring the electrical power system of the Hubble Space Telescope [PDF]
The design and the prototype for the expert system for the Hubble Space Telescope's electrical power system are discussed. This prototype demonstrated the capability to use real time data from a 32k telemetry stream and to perform operational health and ...
Eddy, Pat
core +1 more source
Nonprofits in Rural America: Overcoming the Resource Gap [PDF]
, 2009 Nonprofit organizations across the United States serve the needs of rural communities in critically important ways. Yet the conditions under which they operate, challenging in the best of times, become even more difficult under national economic stress ...
Barry Newstead, Pat Wu
core