Results 201 to 210 of about 39,769 (255)
Clonidine Inhibits Interictal-like Epileptiform Events in Prefrontal Cortex Pyramidal Neurons. [PDF]
Int J Mol SciKołba W, Herbst D, Szulczyk B.
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Capacitance measurements with the patch-clamp technique.
Seibutsu Butsuri, 1989 openaire +2 more sources
APOE4 and doxorubicin impair inhibitory interneuron function and homeostatic regulation in the entorhinal cortex. [PDF]
PLoS OneLuo N +6 more
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Patch Clamp Techniques for Plant Cells
2012The study of electrophysiological processes at the molecular level, with exquisite sensitivity and full control over the experimental conditions, is possible with the patch clamp technique. A concise overview is given of the different configurations that are used with the technique.
J Theo M Elzenga, Elzenga J Theo M
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Conventional Micropipette-Based Patch Clamp Techniques
Methods in Molecular Biology, 2013The patch clamp technique revolutionized the study of ion channels and is considered the gold standard of measuring ion channel activity, from the academic laboratory to industrial-scale drug screening. This technique enables the study of ion channels, from single molecules up to the whole-cell ion channel population, and in their native environment ...
Jonathan D, Lippiat, David C, Wrighton
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The patch clamp technique: Principles and technical considerations
Journal of Veterinary Cardiology, 2007The development of techniques that allow the high fidelity measurement of small scale ionic currents ushered in a new era of investigation into the role of ion channels in the physiologic and pathophysiologic function of excitable tissue. Based upon the formation of a high resistance (gigaohm) seal with the membrane of the cell being studied, these ...
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Neurosurgery, 1995
The introduction of the patch clamp technique less than two decades ago revolutionized the study of cellular physiology by providing a high-resolution method of observing the function of individual ionic channels in a variety of normal and pathological cell types.
L K, Liem +3 more
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The introduction of the patch clamp technique less than two decades ago revolutionized the study of cellular physiology by providing a high-resolution method of observing the function of individual ionic channels in a variety of normal and pathological cell types.
L K, Liem +3 more
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1995
In this chapter, I shall explain how to set-up a patch-clamp technique. The aim is to guide researchers in their initial steps in the field of electrophysiology, describing the instrumentation needed, as well as the technique itself. This chapter has been written assuming that the reader has a basic knowledge of electrophysiology.
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In this chapter, I shall explain how to set-up a patch-clamp technique. The aim is to guide researchers in their initial steps in the field of electrophysiology, describing the instrumentation needed, as well as the technique itself. This chapter has been written assuming that the reader has a basic knowledge of electrophysiology.
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The Patch Clamp Technique in Ion Channel Research
Current Pharmaceutical Biotechnology, 2004To understand the pathogenesis of a given ion channel disorder, knowledge of the mutation alone is insufficient, instead, the description of the associated functional defect is decisive. The patch clamp technique enables to achieve this both in native tissue as well as heterologous expression systems. By this technique, structure-function relationships
K, Jurkat-Rott, F, Lehmann-Horn
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