Results 41 to 50 of about 752,311 (360)
Nanoscale-targeted patch-clamp recordings of functional presynaptic ion channels [PDF]
, 2013 Important modulatory roles have been attributed to presynaptic NMDA receptors (NMDARs) located on cerebellar interneuron terminals. Evidence supporting a presynaptic location includes an increase in the frequency of mini events following the application ...
Benton, DCH +4 more
core +1 more source
Whole-cell and Perforated Patch-clamp Recordings from Acutely-isolated Murine Sino-atrial Node Cells
Bio-Protocol, 2020 Cardiac pacemaker cells of the sino-atrial node are responsible for the initiation of the heart beat and express an array of ion channels. The patch-clamp technique is the gold standard method for investigating the function of ion channels expressed in ...
Qadeer Aziz +2 more
doaj +1 more source
Exploring the Coordination of Cardiac Ion Channels With Action Potential Clamp Technique
Frontiers in Physiology, 2022 The patch clamp technique underwent continual advancement and developed numerous variants in cardiac electrophysiology since its introduction in the late 1970s. In the beginning, the capability of the technique was limited to recording one single current
Balázs Horváth +9 more
doaj +1 more source
Lack of direct evidence for a functional role of voltage-operated calcium channels in juxtaglomerular cells [PDF]
, 1990 In this study we have examined the role of voltage-gated calcium channels in the regulation of calcium in juxtaglomerular cells. Using a combination of patch-clamp and single-cell calcium measurement we obtained evidence neither for voltage-operated ...
Chegini, S. +3 more
core +1 more source
Protocol: optimised electrophyiological analysis of intact guard cells from arabidopsis [PDF]
, 2012 Genetic resources available for Arabidopsis thaliana make this species particularly attractive as a model for molecular genetic studies of guard cell homeostasis, transport and signalling, but this facility is not matched by accessible tools for ...
Blatt, M.R. +4 more
core +3 more sources
Frontiers in Aging Neuroscience, 2021 A patch-clamp recording in slices generated from the brain or the spinal cord has facilitated the exploration of neuronal circuits and the molecular mechanisms underlying neurological disorders.
Yang Li +5 more
doaj +1 more source
Errors in the measurement of voltage-activated ion channels in cell-attached patch-clamp recordings [PDF]
, 2011 Patch-clamp recording techniques have revolutionized understanding of the function and sub-cellular location of ion channels in excitable cells. The cell-attached patch-clamp configuration represents the method of choice to describe the endogenous ...
Williams, Stephen R., Wozny, Christian
core +1 more source
bioRxiv, 2019 Comparing neuronal microcircuits across different brain regions, species and individuals can reveal common and divergent principles of network computation.
Yangfan Peng +5 more
semanticscholar +1 more source
Biotechnology Reports, 2015 Kv2.1, the voltage-gated ion channel, is ubiquitously expressed in variety of tissues and dysfunction of this ion channel is responsible for multiple diseases. Electrophysiological properties of ion channels are so far characterized with eukaryotic cells
Kyoko Kikuchi +3 more
doaj +1 more source
Increase in neuroexcitability of unmyelinated C-type vagal ganglion neurons during initial postnatal development of visceral afferent reflex functions [PDF]
, 2013 BACKGROUND: Baroreflex gain increase up closely to adult level during initial postnatal weeks, and any interruption within this period will increase the risk of cardiovascular problems in later of life span. We hypothesize that this short period after
Cao, Pan‐Xiang +13 more
core +1 more source