Protocol: optimised electrophyiological analysis of intact guard cells from arabidopsis [PDF]
, 2012 Genetic resources available for Arabidopsis thaliana make this species particularly attractive as a model for molecular genetic studies of guard cell homeostasis, transport and signalling, but this facility is not matched by accessible tools for ...
Blatt, M.R. +4 more
core +3 more sources
A nongenomic mechanism for progesterone-mediated immunosuppression: Inhibition of K+ channels, Ca2+ signaling, and gene expression in T lymphocytes [PDF]
, 1998 The mechanism by which progesterone causes localized suppression of the immune response during pregnancy has remained elusive. Using human T lymphocytes and T cell lines, we show that progesterone, at concentrations found in the placenta, rapidly and ...
Beer +54 more
core +3 more sources
3D bioprinted human cortical neural constructs derived from induced pluripotent stem cells [PDF]
, 2019 Bioprinting techniques use bioinks made of biocompatible non-living materials and cells to build 3D constructs in a controlled manner and with micrometric resolution.
Benedetti, Maria Cristina +9 more
core +1 more source
Single-channel measurements of an N-acetylneuraminic acid-inducible outer membrane channel in Escherichia coli [PDF]
, 2012 NanC is an Escherichia coli outer membrane protein involved in sialic acid (Neu5Ac, i.e., N-acetylneuraminic acid) uptake. Expression of the NanC gene is induced and controlled by Neu5Ac. The transport mechanism of Neu5Ac is not known.
Eisenberg, Bob +4 more
core +1 more source
Biotechnology Reports, 2015 Kv2.1, the voltage-gated ion channel, is ubiquitously expressed in variety of tissues and dysfunction of this ion channel is responsible for multiple diseases. Electrophysiological properties of ion channels are so far characterized with eukaryotic cells
Kyoko Kikuchi +3 more
doaj +1 more source
Protocol for pressure-clamped patch-clamp recording at the node of Ranvier of rat myelinated nerves
STAR Protocols, 2021 Summary: The patch-clamp recording technique is indispensable for studying ion channel functions of cells but is challenging to apply to the node of Ranvier, a key site where action potentials are conducted along myelinated nerves.
Hirosato Kanda +3 more
doaj +1 more source
A geographically distributed bio-hybrid neural network with memristive plasticity [PDF]
, 2017 Throughout evolution the brain has mastered the art of processing real-world inputs through networks of interlinked spiking neurons. Synapses have emerged as key elements that, owing to their plasticity, are merging neuron-to-neuron signalling with ...
Corna, Andrea +10 more
core +1 more source
Structure of an archaeal PCNA1-PCNA2-FEN1 complex: elucidating PCNA subunit and client enzyme specificity. [PDF]
, 2006 The archaeal/eukaryotic proliferating cell nuclear antigen (PCNA) toroidal clamp interacts with a host of DNA modifying enzymes, providing a stable anchorage and enhancing their respective processivities.
Andrew S. Doré +48 more
core +4 more sources
Dynaflow ™ 48, a microfluidic chip solution for increasing throughput and data quality in patch-clamp-based drug screening [PDF]
, 2006 Ion channels are transm embrane proteins, found in virtually all cell types throughout the human body. Ion channels underlie neural communication, memory, behavior, every movement and heartbeat, and are as such prone to cause disease if malfunctioning.
Granfeldt, Daniel +4 more
core
Increase in neuroexcitability of unmyelinated C-type vagal ganglion neurons during initial postnatal development of visceral afferent reflex functions [PDF]
, 2013 BACKGROUND: Baroreflex gain increase up closely to adult level during initial postnatal weeks, and any interruption within this period will increase the risk of cardiovascular problems in later of life span. We hypothesize that this short period after
Cao, Pan‐Xiang +13 more
core +2 more sources