Results 31 to 40 of about 47,082 (157)

REGULAÇÃO DE PRODUTOS PARA SAÚDE: EM BUSCA DAS MELHORES PRÁTICAS

Revista de Direito Sanitário, 2017
A seção "Tema em Debate" deste número da Revista de Direito Sanitário centra-se novamente no marco regulatório existente no Brasil na área de produtos para a saúde.
Daniela Trejos Vargas
doaj   +1 more source

Criteria for Control and Remission of Respiratory Allergic Disease With Allergen Immunotherapy: A Delphi Consensus

Clinical and Translational Allergy, Volume 16, Issue 8, August 2026.
Expert consensus using a Delphi methodology proposed definitions of control and remission for allergic rhinitis, conjunctivitis and asthma in the context of allergen immunotherapy. These consensus‐based criteria integrate symptoms, medication use, patient‐reported outcomes and objective measures to support a more structured assessment of treatment ...
Eloína González‐Mancebo, Juan María Beitia Mazuecos, Ana I Tabar Purroy, Mar Gandolfo‐Cano, Adriana Izquierdo‐Domínguez, María José Castillo Marchuet, Cristina Cuevas Bravo, Leticia Domínguez Cereijo, Alicia Enríquez‐Matas, Ignacio Esteban Gorgojo, Adrián Germán Sánchez, Alba Juárez Guerrero   +11 more
wiley   +1 more source

Vobramitamab duocarmazine, an anti–B7‐H3 antibody–drug conjugate, in patients with advanced solid tumors: Final results of a phase 1 cohort expansion

Cancer, Volume 132, Issue 15, 1 August 2026.
Abstract Background Vobramitamab duocarmazine is an investigational antibody–drug conjugate (ADC) targeting B7 homolog 3 (B7‐H3) with a cytotoxic duocarmycin‐based DNA‐alkylating payload. This study evaluated its safety and antitumor activity in advanced solid tumors.
Eugene Shenderov, Manish R. Sharma, Elena Garralda, John Powderly, Iwona Ługowska, Alexander Spira, Marc Cucurull Salamero, Sekwon Jang, Rasha Cosman, John Shen, Wen Xu, Piotr J. Wysocki, Rodryg Ramlau, Emmanuel S. Antonarakis, Andrew J. Weickhardt, Jakub Żołnierek, Emiliano Calvo, Enxu Zhao, Chet Bohac, Ashley Ward, Girish Mallesara   +20 more
wiley   +1 more source

Policy Networks and Policy Entrepreneurship in the EU: Explaining Structural Policy Change in Pharmaceutical Innovation Incentives and Health Technology Assessment

European Policy Analysis, Volume 12, Issue 4, Fall 2026.
ABSTRACT Policy process research has excelled in explaining structural policy change within national settings, but extensions and applications to the EU level have long proven challenging for scholars. Given that the EU is currently experiencing its longest period of Treaty stability since the 1980s—having evolved into a sui generis political system ...
Vassilis Karokis‐Mavrikos
wiley   +1 more source

Depósitos de patentes pelas IES de Santa Catarina: um estudo métrico da inovação [PDF]

, 2013
TCC (graduação) - Universidade Federal de Santa Catarina, Centro de Ciências da Educação, Curso de Biblioteconomia.O desenvolvimento em inovação pelas Instituições de Ensino Superior e de Pesquisa de Santa Catarina vive um crescimento.
Moraes, Clarissa Kellermann de, Moraes, Clarissa Kellerman de   +1 more
core  

Patentes farmacéuticas y acuerdos comerciales

, 2009
Objetivos: Revisar las implicaciones relacionadas con patentes farmacéuticas que han surgido en Chile desde la firma de acuerdos con la Organización Mundial del Comercio (OMC) y la suscripción de tratados de libre comercio con Estados Unidos y ...
Carbajal, Y
core   +1 more source

Nanostructured and Functionalized Calcium Hydroxyapatite Enhances Collagen Production by Human Dermal Fibroblasts Compared With Microstructured Counterparts In Vitro

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 8, August 2026.
Nanostructured, lactose‐functionalized calcium hydroxyapatite (nanoCaHA) was produced by nanospray drying, yielding submicron, amorphous, carbonated particles with improved physicochemical properties. NanoCaHA was biocompatible and outperformed microstructured CaHA in stimulating collagen‐related gene expression and total collagen production in human ...
Elizabeth Cristina Iseke Bispo, Stefhani Martins de Barcelos, Jonad Logan A. Contarato, Atailson Oliveira da Silva, Rafael Vieira Rocho, Ana Clara Nogueira Brathwaite, Venâncio Alves Amaral, Paula Martins de Oliveira, Maria Victória Souto‐Silva, Graziella Anselmo Joanitti, Marcilio Cunha‐Filho, Guilherme Martins Gelfuso, Juliana Lott de Carvalho, Felipe Saldanha‐Araújo, Taís Gratieri   +14 more
wiley   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

Phytotherapy Research, Volume 40, Issue 7, Page 4676-4709, July 2026.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández, Sara Elis Bianchi, Flávia Nathiely Silveira Fachel, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +5 more
wiley   +1 more source

A inovação nas incubadoras tecnológicas :: uma análise sob a ótica das patentes / [PDF]

, 1999
Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro Sócio-Econômico.Resultado de uma pesquisa realizada com 73 empresas residentes em 9 incubadoras tecnológicas no Brasil, a proposta deste estudo é analisar as inovações desenvolvidas ...
Prado, Evandro José da Silva
core  

Characterizing circadian rest–activity rhythm patterns across Alzheimer's disease continuum in Down syndrome

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Sleep and circadian rest–activity rhythm (RAR) disruption may bidirectionally relate to Alzheimer's disease (AD). Down syndrome (DS), the most common genetic cause of AD, presents sleep disorders, yet RAR patterns across the DS‐associated AD continuum remain uncharacterized. METHODS We analyzed 7‐day wrist actigraphy in 140 adults
Sandra Giménez, Lídia Vaqué‐Alcázar, Susana Clos, Bessy Benejam, Maria Carmona‐Iragui, Lucía Maure‐Blesa, Laura Videla, Nuole Zhu, Miren Altuna, Javier Arranz, Isabel Barroeta, Íñigo Rodríguez‐Baz, Alexandre Bejanin, Ana Bueno, Susana Fernandez, Laura del Hoyo Soriano, Lucia Pertierra, Daniel Alcolea, Bruce Miller, Lea T. Grinberg, Joaquin Ruiz, Christos Panagiotis Lisgaras, Hau‐Tieng Wu, Alberto Lleó, Ricardo S. Osorio, Esther M. Blessing, Juan Fortea   +26 more
wiley   +1 more source