Results 41 to 50 of about 6,351 (173)

¿Libertad o monopolio? Patentes, tratados comerciales y acceso a tratamientos con antirretrovirales [PDF]

, 2006
En la actualidad, los gobiernos de numerosos países de ingresos medios y bajos están estableciendo regulaciones que hacen más estricta su legislación nacional en materia de propiedad intelectual.
Castro, Arachu, Westerhaus, Michael
core  

El derecho de acceso a los medicamentos y el derecho de patente en los países en desarrollo [PDF]

, 2016
El artículo parte de las dificultades que experimentan los ciudadanos de países en desarrollo para acceder a medicamentos esenciales, nuevos (protegidos por patente) y de calidad.
Ortega Gómez, Marta
core   +2 more sources

Impact of C18 Epimerization of Indole‐ and Pyrazole‐Fused 18β‐Glycyrrhetinic Acid Derivatives on PTP1B and TCPTP Inhibitory Activity: Synthesis, In Vitro, and In Silico Studies

ChemMedChem, Volume 20, Issue 22, November 18, 2025.
The indole derivative (FC‐114) and the N‐phenylpyrazole (FC‐122) of glycyrrhetinic acid are both potent inhibitors of the Protein Tyrosine Phosphatase 1B, with IC50 values of 0.48 μM and 1.15 μM, respectively. However, their activity decreases by up to four times when the 18β‐H position is epimerized to 18α‐H or when the carbonyl group at the C11 ...
Ledy De‐la‐Cruz‐Martínez, Rosendo Martínez‐Arellano, Mitzi López‐Sánchez, José G. Alvarado‐Rodríguez, Jesús Martin Torres‐Valencia, David Equihua‐González, Julio‐César Almanza‐Pérez, Jaime Pérez‐Villanueva, Martín González‐Andrade, José C. Páez‐Franco, Francisco Cortés‐Benítez   +10 more
wiley   +1 more source

OS MEDICAMENTOS E AS PATENTES PIPELINE: CONVERGÊNCIAS E DISTANCIAMENTOS ENTRE A ORDEM JURÍDICA CONSTITUIÇÃO BRASILEIRA E AS PREVISÕES ESTRANGEIRAS

Revista Direitos Humanos e Democracia, 2016
O presente trabalho visa aquilatar uma análise geral sobre o tema “patente” em especial a pipiline, bem como suas formas de concessão e os principais acontecimentos relacionados à evolução do tema em na ordem jurídica brasileira e no cenário estrangeiro.
Dirceu Pereira Siqueira, Bruna Fernandes Alves   +1 more
doaj   +1 more source

Estructuras monopolísticas y análisis industrial en España : el caso de la industria farmacéutica [PDF]

, 1977
The monopolistic structures of industrial markets in Spain are ever increasingly complex. The need to understand them properly, and to design an economic policy which is congruent to their nature, require an effort in the field of analysis, and an ...
Lobo, Félix
core   +1 more source

Study of brain perfusion in adults with Down syndrome along the Alzheimer's disease continuum

Alzheimer's &Dementia, Volume 21, Issue 9, September 2025.
Abstract INTRODUCTION We assessed pseudo‐continuous arterial spin labeling (pCASL) sensitivity to detect changes in cerebral blood flow (CBF) in adults with Down syndrome (DS) along the Alzheimer's disease (AD) continuum and explored the similarity with sporadic AD (sAD) hypoperfusion profile.
Maria Franquesa‐Mullerat, Alejandra O. Morcillo‐Nieto, José Enrique Arriola‐Infante, Sara E. Zsadanyi, Lídia Vaqué‐Alcázar, Mateus Rozalem‐Aranha, Javier Arranz, Íñigo Rodríguez‐Baz, Lucia Maure‐Blesa, Laura Videla, Isabel Barroeta, Laura Del Hoyo Soriano, Bessy Benejam, Susana Fernández, Aida Sanjuan Hernandez, Sandra Giménez, Daniel Alcolea, Olivia Belbin, Alberto Lleó, María Carmona‐Iragui, Juan Fortea, Alexandre Bejanin   +21 more
wiley   +1 more source

Propiedad intelectual y patentes sobre usos medicinales en conocimientos tradicionales

Investigación Agraria, 2018
En este trabajo se analiza el conocimiento tradicional sobre las supuestas propiedades medicinales de plantas y sus usos, como parte de los bienes comunes, que tiene la protección del derecho interno y del derecho internacional. Se consideran los usos de
Ramón Fogel
doaj   +1 more source

Nutraceutical Blends Promote Weight Loss, Inflammation Reduction, and Better Sleep: The Role of Faecalibacterium prausnitzii in Overweight Adults–A Double‐Blind Trial

Molecular Nutrition &Food Research, Volume 69, Issue 17, September 2025.
This study explored how a 90‐day nutraceutical blend with prebiotics, minerals, and silymarin affects the gut‐brain axis in overweight adults. Results showed improved gut microbiota, reduced inflammation, and better sleep, mood, and quality of life, suggesting a strong link between gut health and mental well‐being.
Aline Boveto Santamarina, Victor Nehmi Filho, Jéssica Alves de Freitas, Lucas Augusto Moysés Franco, Roberta Cristina Martins, Joyce Vanessa Fonseca, José Antônio Orellana Turri, Mariana Tedesco Hufnagel, Daniel Pecoraro Demarque, Bruna Fernanda Rio Branco da Silva, Arianne Fagotti Gusmão, Eloísa Helena Ribeiro Olivieri, Erica de Souza, Esther Alves de Souza, José Pinhata Otoch, Ana Flávia Marçal Pessoa   +15 more
wiley   +1 more source

Reflexiones sobre las nuevas directivas de patentabilidad para invenciones farmacéuticas

Revista Iberoamericana de la Propiedad Intelectual, 2013
Lo que se pretende es realizar un ejercicio de reflexión sobre la aplicación del sistema de patentes al ámbito de los medicamentos farmacéuticos tomando como tópico disparador la Resolución Conjunta citada.
Pablo Tomás Lamas
doaj  

Gas Chromatography–Mass Spectroscopy (GC–MS) Simultaneous Determination of Limonene, Linalool, and Linalyl Acetate in Rat Plasma Following Transdermal Administration of the Essential Oil of Bergamot Loaded Onto Solid Lipid Nanoparticles (NanoBEO)

Phytotherapy Research, Volume 40, Issue 2, Page 488-492, February 2026.
Luigi A. Morrone, Laura Rombolà, Antonella Leggio, Emilia L. Belsito, Ludovica Scorzafave, Enrica De Rasis, Martina Pagliaro, Kengo Hamamura, Takafumi Hayashi, Giacinto Bagetta, Maria Tiziana Corasaniti, Damiana Scuteri   +11 more
wiley   +1 more source