Results 1 to 10 of about 6,734 (227)

Role of the upper airway microbiota in respiratory virus and bacterial pathobiont dynamics in the first year of life [PDF]

Nature Communications
The mechanisms by which respiratory viruses predispose to secondary bacterial infections remain poorly characterized. Using 2,409 nasopharyngeal swabs from 300 infants enrolled in a prospective cohort study in Botswana, we perform a detailed analysis of ...
Matthew S. Kelly, Pixu Shi, Sifelane C. Boiditswe, Emily Qin, Andrew P. Steenhoff, Tiny Mazhani, Mohamed Z. Patel, Coleen K. Cunningham, John F. Rawls, Kathy Luinstra, Jodi Gilchrist, Julia Maciejewski, Jillian H. Hurst, Patrick C. Seed, David Bulir, Marek Smieja   +15 more
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Nasal pathobiont abundance does not differ between dairy cattle with or without clinical symptoms of bovine respiratory disease [PDF]

Animal Microbiome
Background Bovine respiratory disease (BRD) remains a significant health and economic problem to the dairy cattle industry. Multiple risk factors contribute to BRD susceptibility including the bacterial pathobionts Mannheimia haemolytica, Pasteurella ...
Ruth Eunice Centeno-Delphia, Erica A. Long, Audrey C. Ellis, Sarah Hofmann, Kara Mosier, Noelmi Ulloa, Johnnie Junior Cheng, Andrew Richards, Jacquelyn P. Boerman, Jennifer Koziol, Mohit S. Verma, Timothy A. Johnson   +11 more
doaj   +2 more sources

Human colitis-associated colorectal carcinoma progression is accompanied by dysbiosis with enriched pathobionts [PDF]

Gut Microbes
Dysbiosis and pathobionts contribute to inflammation and the risk of colitis-associated carcinoma (CAC) in animal models, but their roles in humans with this uncommon disease are unknown.
Amr H. Masaadeh, Mohamed Eletrebi, Bishal Parajuli, Nicola De Jager, Dustin E. Bosch   +4 more
doaj   +2 more sources

From Global to Nano: A Geographical Perspective of Aggregatibacter actinomycetemcomitans [PDF]

Pathogens
The periodontal disease pathobiont Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans) may exert a range of detrimental effects on periodontal diseases in general and, more specifically, with the initiation and progression of Localized Stage
Mark I. Ryder, Daniel H. Fine, Annelise E. Barron   +2 more
doaj   +2 more sources

Klebsiella ARO112 promotes microbiota recovery, pathobiont clearance and prevents inflammation in IBD mice [PDF]

Nature Communications
Precise microbiota modulation towards improving immune function and metabolic homeostasis is a major goal in clinical research. It is also critical for reducing pathogen invasion or pathobiont expansion, contributors to epidemic Inflammatory Bowel ...
Vitor Cabral, Rita A. Oliveira, Margarida B. Correia, Miguel F. Pedro, Marc García-Garcerá, Carles Ubeda, Karina B. Xavier   +6 more
doaj   +2 more sources

Dysbiosis From a Microbial and Host Perspective Relative to Oral Health and Disease

Frontiers in Microbiology, 2021
The significance of microbiology and immunology with regard to caries and periodontal disease gained substantial clinical or research consideration in the mid 1960's.
Carla Cugini, Narayanan Ramasubbu, Vincent K. Tsiagbe, Daniel H. Fine   +3 more
doaj   +1 more source

Absence of Bacteria Permits Fungal Gut-To-Brain Translocation and Invasion in Germfree Mice but Ageing Alone Does Not Drive Pathobiont Expansion in Conventionally Raised Mice

Frontiers in Aging Neuroscience, 2022
Age-associated changes in the structure of the intestinal microbiome and in its interaction with the brain via the gut-brain axis are increasingly being implicated in neurological and neurodegenerative diseases.
Aimée Parker, Steve A. James, Catherine Purse, Arlaine Brion, Andrew Goldson, Andrea Telatin, David Baker, Simon R. Carding   +7 more
doaj   +1 more source

The unforeseen intracellular lifestyle of Enterococcus faecalis in hepatocytes

Gut Microbes, 2022
Enterococcus faecalis is a bacterial species present at a subdominant level in the human gut microbiota. This commensal turns into an opportunistic pathogen under specific conditions involving dysbiosis and host immune deficiency. E.
Natalia Nunez, Aurélie Derré-Bobillot, Nicolas Trainel, Goran Lakisic, Alexandre Lecomte, Françoise Mercier-Nomé, Anne-Marie Cassard, Hélène Bierne, Pascale Serror, Cristel Archambaud   +9 more
doaj   +1 more source

Comparative analysis of the red-complex organisms and recently identified periodontal pathogens in the subgingival plaque of diabetic and nondiabetic patients with severe chronic periodontitis

Journal of Indian Society of Periodontology, 2023
Aim: This analytical case–control study sought to evaluate the presence of the recently established putative periodontal pathogen organisms, Filifactor alocis and Fretibacterium fastidiosum, against the levels of the already established red-complex ...
Divya Shree Pandian, Dhayanad John Victor, Priyanka Cholan, P SG Prakash, Sangeetha Subramanian, Sumi Priyadarshini Shankar   +5 more
doaj   +1 more source

Dietary Emulsifiers Directly Impact Adherent-Invasive E. coli Gene Expression to Drive Chronic Intestinal Inflammation

Cell Reports, 2020
Summary: Dietary emulsifiers carboxymethylcellulose (CMC) and polysorbate-80 (P80) disturb gut microbiota, promoting chronic inflammation. Mice with minimal microbiota are protected against emulsifiers’ effects, leading us to hypothesize that these ...
Emilie Viennois, Alexis Bretin, Philip E. Dubé, Alexander C. Maue, Charlène J.G. Dauriat, Nicolas Barnich, Andrew T. Gewirtz, Benoit Chassaing   +7 more
doaj   +1 more source