Streptococcus suis – The “Two Faces” of a Pathobiont in the Porcine Respiratory Tract
Streptococcus (S.) suis is a frequent early colonizer of the upper respiratory tract of pigs. In fact, it is difficult to find S. suis-free animals under natural conditions, showing the successful adaptation of this pathogen to its porcine reservoir host.
Désirée Vötsch +3 more
doaj +1 more source
Association of nine pathobionts with periodontitis in four South American and European countries
Aim Our aim was to compare the prevalence and load of nine pathobionts in subgingival samples of healthy individuals and periodontitis patients from four different countries.Methods Five hundred and seven subgingival biofilm samples were collected from ...
Gerard Àlvarez +12 more
doaj +1 more source
A systematic approach to cancer: evolution beyond selection. [PDF]
Cancer is typically scrutinized as a pathological process characterized by chromosomal aberrations and clonal expansion subject to stochastic Darwinian selection within adaptive cellular ecosystems.
Miller, William B, Torday, John S
core +1 more source
Clinical concentrations of peroxidases cause dysbiosis in invitro oral biofilms [PDF]
Background and Objective: Little is known about the initiation of dysbiosis in oral biofilms, a topic of prime importance for understanding the etiology of, and preventing, periodontitis.
Agar +36 more
core +2 more sources
Pathobionts of the gastrointestinal microbiota and inflammatory disease [PDF]
Our immune system is charged with the vital mission of identifying invading pathogens and mounting proper inflammatory responses. During the process of clearing infections, the immune system often causes considerable tissue damage. Conversely, if the target of immunity is a member of the resident microbiota, uncontrolled inflammation may lead to host ...
Chow, Janet +2 more
openaire +3 more sources
The illness ME/CFS has been repeatedly tied to infectious agents such as Epstein Barr Virus. Expanding research on the human microbiome now allows ME/CFS-associated pathogens to be studied as interacting members of human microbiome communities.
Amy Proal, Trevor Marshall
doaj +1 more source
Oral pathobiont induces systemic inflammation and metabolic changes associated with alteration of gut microbiota. [PDF]
Periodontitis has been implicated as a risk factor for metabolic disorders such as type 2 diabetes, atherosclerotic vascular diseases, and non-alcoholic fatty liver disease. Although bacteremias from dental plaque and/or elevated circulating inflammatory
Arimatsu, Kei +10 more
core +2 more sources
Galleria mellonella: A Novel Invertebrate Model to Distinguish Intestinal Symbionts From Pathobionts
Insects and mammals share evolutionary conserved innate immune responses to maintain intestinal homeostasis. We investigated whether the larvae of the greater wax moth Galleria mellonella may be used as an experimental organism to distinguish between ...
Anna Lange +6 more
doaj +1 more source
Identification of Allobaculum mucolyticum as a novel human intestinal mucin degrader
The human gut microbiota plays a central role in intestinal health and disease. Yet, many of its bacterial constituents are functionally still largely unexplored.
Guus H. van Muijlwijk +7 more
doaj +1 more source
A Hen in the Wolf Den: A Pathobiont Tale [PDF]
Disruption of the gut microbiota is thought to contribute to disease onset in individuals with a genetic predisposition to autoimmunity. In a recent issue of Science, Manfredo Vieira et al. (2018) identify translocation of the gut commensal Enterococcus gallinarum into the liver as a trigger for the autoimmune disease systemic lupus erythematous.
Matteo M, Guerrini +2 more
openaire +2 more sources

