Results 51 to 60 of about 6,734 (227)

Periodontal microbiology and microbial etiology of periodontal diseases: Historical concepts and contemporary perspectives

Periodontology 2000, EarlyView., 2023
Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis, Daniel Belstrøm, Sigrun Eick, Ulvi K. Gursoy, Anders Johansson, Eija Könönen   +5 more
wiley   +1 more source

Targeting a cysteine protease from a pathobiont alleviates experimental arthritis [PDF]

Arthritis Research & Therapy, 2020
Abstract Background Several lines of evidence suggest that the pathobiont Porphyromonas gingivalis is involved in the development and/or progression of auto-inflammatory diseases. This bacterium produces cysteine proteases, such as gingipain RgpA, endowed with the potential to induce significant bone loss in model ...
Hsin-Yi Peng, Shih-Yao Chen, Shih-Hong Siao, Jinghua Tsai Chang, Ting-Yin Xue, Yi-Hsuan Lee, Ming-Shiou Jan, Gregory J. Tsay, Moncef Zouali   +8 more
openaire   +3 more sources

Control of pathogens and pathobionts by the gut microbiota [PDF]

Nature Immunology, 2013
A dense resident microbial community in the gut, referred as the commensal microbiota, coevolved with the host and is essential for many host physiological processes that include enhancement of the intestinal epithelial barrier, development of the immune system and acquisition of nutrients.
Nobuhiko, Kamada, Grace Y, Chen, Naohiro, Inohara, Gabriel, Núñez   +3 more
openaire   +2 more sources

Intestinal Microbiota Composition of Interleukin-10 Deficient C57BL/6J Mice and Susceptibility to Helicobacter hepaticus-Induced Colitis [PDF]

, 2013
The mouse pathobiont Helicobacter hepaticus can induce typhlocolitis in interleukin-10-deficient mice, and H. hepaticus infection of immunodeficient mice is widely used as a model to study the role of pathogens and commensal bacteria in the pathogenesis ...
A Burich, A Giongo, A Klindworth, A Mangerich, Achim D. Gruber, AK Benson, André Bleich, Birgit Brenneke, Christine Josenhans, Daniel Eibach, DN Frank, E Elinav, E Pruesse, EJ Baron, EV Kulagina, FE Dewhirst, Friederike Kops, G Büchler, H Ochman, Ines Yang, J Chow, J Vaahtovuo, JA Peña, James G. Fox, Jessika Schulze, JG Fox, JG Fox, JG Fox, JL Lofgren, JM Ward, JR White, JS Pratt, K Katoh, KJ Maloy, L Bartonickova, LA Dieleman, M Ciszek-Lenda, M Hoffmann, M Rajilić-Stojanović, Markus M. Heimesaat, MC Kullberg, MC Kullberg, MC Kullberg, MK Friswell, MR Hufeldt, MSP Azevedo, MT Whary, N Segata, PB Eckburg, PD Schloss, PD Schloss, PJ Turnbaugh, Q Wang, RC Edgar, RC Edgar, RJ Cahill, S Devkota, S Finegold, S Nell, S Suerbaum, Sabrina Woltemate, Sebastian Suerbaum, SK Mazmanian, SR Boutin, SR Boutin, Sureshkumar Muthupalani, T Kuehbacher, T Sterzenbach, T Sterzenbach, UK Schumacher, VB Young, W Jia, W Nicklas, WS Garrett, Y Cai, Y Liu, Z Ge, Z Ge, Z Ge, Z Ge, Z Ge, Z Zhang   +81 more
core   +3 more sources

Gut microbiota facilitates dietary heme-induced epithelial hyperproliferation by opening the mucus barrier in colon [PDF]

, 2015
Colorectal cancer risk is associated with diets high in red meat. Heme, the pigment of red meat, induces cytotoxicity of colonic contents and elicits epithelial damage and compensatory hyperproliferation, leading to hyperplasia.
Clara Belzer, Giovannucci, Guido J. Hooiveld, Jan Dekker, Lapré, McGarr, Michael Müller, Michiel Kleerebezem, Noortje Ijssennagger, Roelof van der Meer, Saskia W. C. van Mil, Sesink, Sheffner, van Klinken   +13 more
core   +2 more sources

Escherichia coli Pathobionts Associated with Inflammatory Bowel Disease [PDF]

Clinical Microbiology Reviews, 2019
Gut bacteria play a key role in initiating and maintaining the inflammatory process in the gut tissues of inflammatory bowel disease (IBD) patients, by supplying antigens or other stimulatory factors that trigger immune cell activation. Changes in the composition of the intestinal microbiota in IBD patients compared to that in healthy controls and a ...
Hengameh Chloé Mirsepasi-Lauridsen, Bruce Andrew Vallance, Karen Angeliki Krogfelt, Andreas Munk Petersen   +3 more
openaire   +3 more sources

The Inhibitory Effect of Ileal Mucosal Media Originated from FVB/N Mice Strain on Escherichia coli LF82 Invasion

Bezmiâlem Science, 2019
Objective:The aim of this study was to investigate the effect of healthy mucosa on adhesive and invasive properties of AIEC reference strain Escherichia coli (E. coli) LF82.
Hüsamettin AYGÜN, Murat KARAMEŞE, Fikret UYAR   +2 more
doaj   +1 more source

Metagenomic data from cerebrospinal fluid permits tracing the origin and spread of Neisseria meningitidis CC4821 in China

Communications Biology, 2022
Metagenomic data from cerebrospinal fluid was used to genotype Neisseria meningitidis in patients with invasive meningococcal disease and trace the origin of the pathobiont, providing a phylogeographic analysis of the strain’s evolution in China and its ...
Hongbin Chen, Mei Li, Shangyu Tu, Xiaoyang Zhang, Xiaojuan Wang, Yawei Zhang, Chunjiang Zhao, Yinghui Guo, Hui Wang   +8 more
doaj   +1 more source

The role of diet in the aetiopathogenesis of inflammatory bowel disease [PDF]

, 2018
Crohn’s disease and ulcerative colitis, collectively known as IBD, are chronic inflammatory disorders of the gastrointestinal tract. Although the aetiopathogenesis of IBD is largely unknown, it is widely thought that diet has a crucial role in the ...
A Ascherio, A Caspi, A Charlebois, A Ferguson, A Finamore, A Franke, A Poullis, A Racine, A Spor, A Tragnone, A Zhernakova, AL Hernandez, AL Kau, AN Ananthakrishnan, AN Ananthakrishnan, AN Ananthakrishnan, AN Ananthakrishnan, AN Ananthakrishnan, Andrew R. Hart, Andrew T. Chan, AP Simopoulos, AR Hart, AS Prasad, Ashwin N. Ananthakrishnan, B Khor, C Filippo De, C Tysk, C Wu, C Yuan, CA Chapman-Kiddell, CE Hargreaves, CN Williams, CS Probert, D Bharadwaj, D Feskanich, D Kevans, D Kevans, D Knights, DJ Hunter, DJ Hunter, E Bettelli, E Degagne, E Giovannucci, E Riboli, E Rimm, EE Kenny, EI Benchimol, EP Halmos, GA Colditz, GD Wu, GR D’Haens, H Khalili, H Khalili, H Sokol, Hamed Khalili, HE Seifried, HR Rockett, HR Rockett, I Costea, I Ordás, I Romieu, IBD in EPIC Study Investigators, IW Kim, J Breton, J Burisch, J Liang, JL Opstelten, JS Gavaler, K Brown, KW Sloot Van Der, L Zhou, LG Albenberg, LK Stenman, LL Barton, L A David, M Kleinewietfeld, M Martinez-Medina, M Zachos, MC Fantini, MD Kappelman, MD Kappelman, MJ Bonder, MM Bergmann, MM Bergmann, MP Stein, MP Stein, N Ijssennagger, N Ijssennagger, N Risch, N Yosef, N., I. J., NA Molodecky, NA Nagalingam, O Borrelli, P Ferrari, P Jantchou, Paul Lochhead, PC Calder, PG Persson, PJ Turnbaugh, R Eil, RK Leu Le, RK Sellon, S Bao, S Devkota, S Kugathasan, SC Ng, Simon S. M. Chan, SJ London, SS Chan, SS Chan, SS Seregin, T Hudcovic, T Longobardi, T Werner, T Yamamoto, VA Leone, W Turpin, WC Willett, WC Willett, WC Zhang, X Li, XC Morgan   +122 more
core   +1 more source

Influence of probiotic supplementation on the developing microbiota in human preterm neonates

Gut Microbes, 2020
Background Oral administration of probiotic bacteria to preterm neonates has been recommended to prevent the development of necrotizing enterocolitis (NEC).
Niels van Best, Sonja Trepels-Kottek, Paul Savelkoul, Thorsten Orlikowsky, Mathias W. Hornef, John Penders   +5 more
doaj   +1 more source