Results 11 to 20 of about 1,726,520 (358)
What makes pathogens pathogenic [PDF]
Genome Biology, 2008 Metazoans contain multiple complex microbial ecosystems in which the balance between host and microbe can be tipped from commensalism to pathogenicity. This transition is likely to depend both on the prevailing environmental conditions and on specific gene-gene interactions placed within the context of the entire ecosystem.
Fen Z. Hu +4 more
openaire +3 more sources
SaQuant: a real-time PCR assay for quantitative assessment of Staphylococcus aureus
BMC Microbiology, 2021 Background Molecular assays are important tools for pathogen detection but need to be periodically re-evaluated with the discovery of additional genetic diversity that may cause assays to exclude target taxa or include non-target taxa.
Colin Wood +7 more
doaj +1 more source
Pathogens, 2022 It is known that schistosome-derived antigens induce innate and adaptive immune responses that are essential for the formation of hepatic immunopathology. Here, we screened and synthesized four peptides derived from Schistosoma japonicum (S.
Chunxiang Shen +11 more
doaj +1 more source
, 2016 During host-pathogen interactions, a complex web of events is crucial for the outcome of infection. Pathogen recognition triggers powerful cellular signaling events that is translated into the induction and maintenance of innate and adaptive host immunity against infection.
Mesquita, Inês +7 more
openaire +5 more sources
Medical Mycology, 2000 The ever increasing numbers of immunosuppressed individuals has led to a significant increase in the incidence of opportunistic infections, particularly those caused by fungi. The epidemiology of infections caused by the common fungal pathogens such as Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus has been well documented. However,
Ponton, J. +13 more
openaire +3 more sources
Frontiers in Microbiology, 2021 Reactive oxygen species (ROS) are attractive weapons in both antibiotic-mediated killing and host-mediated killing. However, the involvement of ROS in antibiotic-mediated killing and complexities in host environments challenge the paradigm.
Hao Li +5 more
semanticscholar +1 more source
Targeting Antibiotic Tolerance, Pathogen by Pathogen [PDF]
Cell, 2018 Antibiotic tolerance, the capacity of genetically susceptible bacteria to survive the lethal effects of antibiotic treatment, plays a critical and underappreciated role in the disease burden of bacterial infections. Here, we take a pathogen-by-pathogen approach to illustrate the clinical significance of antibiotic tolerance and discuss how the ...
Meylan, Sylvain +2 more
openaire +4 more sources
Nextstrain: real-time tracking of pathogen evolution
bioRxiv, 2017 Summary Understanding the spread and evolution of pathogens is important for effective public health measures and surveillance. Nextstrain consists of a database of viral genomes, a bioinformatics pipeline for phylodynamics analysis, and an interactive ...
J. Hadfield +8 more
semanticscholar +1 more source
Parasites & Vectors, 2018 Background Chemical insecticides have hugely reduced the prevalence of vector-borne diseases around the world, but resistance threatens their continued effectiveness.
Yun Huang +10 more
doaj +1 more source