Results 11 to 20 of about 1,693,186 (355)

MiR-4448 is involved in deltamethrin resistance by targeting CYP4H31 in Culex pipiens pallens

Parasites & Vectors, 2021
Background Culex pipiens (Cx. pipiens) complex, which acts as a vector of viruses and is widespread and abundant worldwide, including West Nile virus, Japanese encephalitis virus, and Sindbis virus, can cause serious vector-borne diseases affecting human
Xixi Li, Shengli Hu, Haitao Yin, Hongbo Zhang, Dan Zhou, Yan Sun, Lei Ma, Bo Shen, Changliang Zhu   +8 more
doaj   +1 more source

MiR-279-3p regulates deltamethrin resistance through CYP325BB1 in Culex pipiens pallens

Parasites & Vectors, 2021
Background The overuse of insecticides to control insect vectors has promoted extensive insecticide resistance in mosquitoes. In this study, the functions of microRNA (miR)-279-3p and its target CYP325BB1 in the regulation of deltamethrin resistance in ...
Xixi Li, Shengli Hu, Hongbo Zhang, Haitao Yin, Huan Wang, Dan Zhou, Yan Sun, Lei Ma, Bo Shen, Changliang Zhu   +9 more
doaj   +1 more source

Therapeutic potential of fucoidan in the reduction of hepatic pathology in murine schistosomiasis japonica

Parasites & Vectors, 2020
Background Hepatic granuloma formation and fibrosis as the consequence of tissue entrapped eggs produced by female schistosomes characterize the pathology of Schistosoma japonicum infection.
Xueqi Bai, Maining Li, Xinyue Wang, Hao Chang, Yangyue Ni, Chen Li, Kaiyue He, Huiquan Wang, Yuxuan Yang, Tian Tian, Min Hou, Minjun Ji, Zhipeng Xu   +12 more
doaj   +1 more source

Physiological characterization of chitin synthase A responsible for the biosynthesis of cuticle chitin in Culex pipiens pallens (Diptera: Culicidae)

Parasites & Vectors, 2021
Background The pathogens transmitted by mosquitoes to humans and animals cause several emerging and resurgent infectious diseases. Increasing insecticide resistance requires rational action to control the target vector population. Chitin is indispensable
Xiaoshan Yang, Yang Xu, Qi Yin, Hongbo Zhang, Haitao Yin, Yan Sun, Lei Ma, Dan Zhou, Bo Shen   +8 more
doaj   +1 more source

SaQuant: a real-time PCR assay for quantitative assessment of Staphylococcus aureus

BMC Microbiology, 2021
Background Molecular assays are important tools for pathogen detection but need to be periodically re-evaluated with the discovery of additional genetic diversity that may cause assays to exclude target taxa or include non-target taxa.
Colin Wood, Jason Sahl, Sara Maltinsky, Briana Coyne, Benjamin Russakoff, David Panisello Yagüe, Jolene Bowers, Talima Pearson   +7 more
doaj   +1 more source

Identification and Characterization of Antigenic Properties of Schistosoma japonicum Heat Shock Protein 90α Derived Peptides

Pathogens, 2022
It is known that schistosome-derived antigens induce innate and adaptive immune responses that are essential for the formation of hepatic immunopathology. Here, we screened and synthesized four peptides derived from Schistosoma japonicum (S.
Chunxiang Shen, Xinyi Zhu, Xuejun Xu, Hao Chang, Yangyue Ni, Chen Li, Kaiyue He, Lin Chen, Lu Chen, Min Hou, Minjun Ji, Zhipeng Xu   +11 more
doaj   +1 more source

Pathogen burden and cortisol profiles over the day [PDF]

, 2009
Hypothalamic-pituitary-adrenocortical (HPA) regulation in adults is influenced by early psychosocial adversity, but the role of infectious disease history is poorly understood.
Bergstrom, S, Gylfe, A, Henderson, B, Shamaei-Tousi, A, Steptoe, A   +4 more
core   +1 more source

Culex pipiens pallens cuticular protein CPLCG5 participates in pyrethroid resistance by forming a rigid matrix

Parasites & Vectors, 2018
Background Chemical insecticides have hugely reduced the prevalence of vector-borne diseases around the world, but resistance threatens their continued effectiveness.
Yun Huang, Qin Guo, Xiaohong Sun, Cheng Zhang, Na Xu, Yang Xu, Dan Zhou, Yan Sun, Lei Ma, Changliang Zhu, Bo Shen   +10 more
doaj   +1 more source

Global analysis of gene expression reveals mRNA superinduction is required for the inducible immune response to a bacterial pathogen. [PDF]

, 2017
The inducible innate immune response to infection requires a concerted process of gene expression that is regulated at multiple levels. Most global analyses of the innate immune response have focused on transcription induced by defined immunostimulatory ...
Barry, Kevin C, Ingolia, Nicholas T, Vance, Russell E   +2 more
core   +3 more sources

Stenoparib, an Inhibitor of Cellular Poly(ADP-Ribose) Polymerase, Blocks Replication of the SARS-CoV-2 and HCoV-NL63 Human Coronaviruses In Vitro

mBio, 2021
New therapeutics are urgently needed in the fight against COVID-19. Repurposing drugs that are either already approved for human use or are in advanced stages of the approval process can facilitate more rapid advances toward this goal.
Nathan E. Stone, Sierra A. Jaramillo, Ashley N. Jones, Adam J. Vazquez, Madison Martz, Lora M. Versluis, Marlee O. Raniere, Haley E. Nunnally, Katherine E. Zarn, Roxanne Nottingham, Ken R. Ng, Jason W. Sahl, David M. Wagner, Steen Knudsen, Erik W. Settles, Paul Keim, Christopher T. French   +16 more
doaj   +1 more source