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Pathogenicity of Enterococci [PDF]
ABSTRACT Enterococci are unusually well adapted for survival and persistence in a variety of adverse environments, including on inanimate surfaces in the hospital environment and at sites of infection. This intrinsic ruggedness undoubtedly played a role in providing opportunities for enterococci to interact with other overtly drug-resistant ...
Michael S. Gilmore+5 more
openaire +3 more sources
Risk assessment for airborne disease transmission by poly-pathogen aerosols [PDF]
In the case of airborne diseases, pathogen copies are transmitted by droplets of respiratory tract fluid that are exhaled by the infectious and, after partial or full drying, inhaled as aerosols by the susceptible. The risk of infection in indoor environments is typically modelled using the Wells-Riley model or a Wells-Riley-like formulation, usually ...
arxiv +1 more source
The dimorphic fungus Candida albicans is both a harmless commensal organism on mucosal surfaces and an opportunistic pathogen. Under certain predisposing conditions, the fungus can overgrow the mucosal microbiome and cause both superficial and life ...
Annika König+2 more
doaj +1 more source
Retroviral integration site selection: a running Gag?
The ability of retroviruses to integrate their genomes into host chromatin is a key step for the completion of their replication cycle. Selection of a suitable chromosomal integration site has been described as a hierarchical mechanism involving both ...
Paul Lesbats, Vincent Parissi
doaj +1 more source
Candidalysin Is the Hemolytic Factor of Candida albicans
Candida albicans produces an important virulence factor, the hypha-associated Ece1-derived secreted peptide toxin candidalysin, which is crucial for the establishment of mucosal and systemic infections. C.
Selene Mogavero+11 more
doaj +1 more source
A Novel Hybrid Iron Regulation Network Combines Features from Pathogenic and Nonpathogenic Yeasts
Iron is an essential micronutrient for both pathogens and their hosts, which restrict iron availability during infections in an effort to prevent microbial growth.
Franziska Gerwien+8 more
doaj +1 more source
Commensal bacteria such as Lactobacillus rhamnosus can inhibit the pathogenicity of the fungus Candida albicans. Here, Alonso-Roman et al. investigate the interplay between C. albicans, L.
Raquel Alonso-Roman+13 more
doaj +1 more source
Vernonanthura brasiliana (L.) H. Rob is a medicinal plant used for the treatment of several infections. This study aimed to evaluate the antileishmanial activity of V. brasiliana leaves using in vitro and in silico approaches. The chemical composition of
Yuri Nascimento Fróes+16 more
doaj +1 more source
Epidemic spreading under mutually independent intra- and inter-host pathogen evolution [PDF]
The dynamics of epidemic spreading is often reduced to the single control parameter $R_0$, whose value, above or below unity, determines the state of the contagion. If, however, the pathogen evolves as it spreads, $R_0$ may change over time, potentially leading to a mutation-driven spread, in which an initially sub-pandemic pathogen undergoes a ...
arxiv +1 more source
Autophagy vitalizes the pathogenicity of pathogenic fungi [PDF]
Plant pathogenic fungi utilize a series of complex infection structures, in particular the appressorium, to gain entry to and colonize plant tissue. As a consequence of the accumulation of huge quantities of glycerol in the cell the appressorium generates immense intracellular turgor pressure allowing the penetration peg of the appressorium to ...
Fei Xu+5 more
openaire +3 more sources