Results 51 to 60 of about 573,776 (343)

A protocol for ultrastructural study of Candida albicans biofilm using transmission electron microscopy

STAR Protocols, 2022
Summary: This protocol describes how to analyze C. albicans biofilm using transmission electron microscopy. We present two approaches to observe the ultrastructure of fungal cells within unperturbed biofilms, as well as an immunogold labeling procedure ...
Thierry Mourer, Martin Sachse, Anastasia D. Gazi, Christophe d’Enfert, Sophie Bachellier-Bassi   +4 more
doaj   +1 more source

In vitro and in vivo screening for novel essential cell-envelope proteins in Pseudomonas aeruginosa [PDF]

, 2015
The Gram-negative bacterium Pseudomonas aeruginosa represents a prototype of multi-drug resistant opportunistic pathogens for which novel therapeutic options are urgently required.
Bragonzi, Alessandra, Fernandez Pinar, Regina, Imperi, Francesco, LO SCIUTO, Alessandra, Ranucci, Serena, Rossi, Alice   +5 more
core   +1 more source

Genetic screening for hypertension and COVID-19 reveals functional variation of SPEG potentially associated with severe COVID-19 in women

Frontiers in Genetics, 2023
The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to more than 6.4 million deaths worldwide.
Yu-Si Luo, Yu-Si Luo, Xiang-Chun Shen, Xiang-Chun Shen, Wei Li, Guo-Feng Wu, Xiao-Meng Yang, Ming-Yang Guo, Fang Chen, Hu-Yan Shen, Ping-Ping Zhang, Han Gao, Ying Nie, Jia-Hong Wu, Rong Mou, Ke Zhang, Ke Zhang, Zhong-Shan Cheng   +17 more
doaj   +1 more source

Melatonin alleviates valproic acid-induced neural tube defects by modulating Src/PI3K/ERK signaling and oxidative stress

Acta Biochimica et Biophysica Sinica, 2023
Neural tube defects (NTDs) represent a developmental disorder of the nervous system that can lead to significant disability in children and impose substantial social burdens.
Liang Yuxiang, Wang Ying, Zhang Xiao, Jin Shanshan, Guo Yuqian, Yu Zhaowei, Xu Xinrui, Shuai Qizhi, Feng Zihan, Chen Binghong, Liang Ting, Ao Ruifang, Li Jianting, Zhang Juan, Cao Rui, Zhao Hong, Chen Zhaoyang, Liu Zhizhen, Xie Jun   +18 more
doaj   +1 more source

Phage inducible islands in the gram-positive cocci [PDF]

, 2016
The SaPIs are a cohesive subfamily of extremely common phage-inducible chromosomal islands (PICIs) that reside quiescently at specific att sites in the staphylococcal chromosome and are induced by helper phages to excise and replicate.
A Bolotin, A Chopin, A Ruzin, B Frígols, BA Duerkop, C Ubeda, C Ubeda, C Ubeda, C Ubeda, C Ubeda, CH O'Callaghan, CM Hamilton, D Straume, D Viana, Davida Smyth, E Charpentier, E Maiques, G Ram, G Ram, Geeta Ram, IT Paulsen, J Chen, J Chen, J Chen, J Scott, J Scott, J-P Claverys, JA Lindsay, John Chen, José R Penadés, JR Penadés, M Kanehisa, MA Tormo, MD Ferrer, Miguel Martí, MÁ Tormo-Más, MÁ Tormo-Más, N Carpena, N Quiles-Puchalt, N Quiles-Puchalt, Nuria Quiles-Puchalt, RC Matos, Richard P Novick, Roser Martínez-Rubio, RP Novick, RP Novick, Suzanne Humphrey, SV Nguyen   +47 more
core   +1 more source

Cytochrome P450 1A1 is essential for the microbial metabolite, Urolithin A-mediated protection against colitis

Frontiers in Immunology, 2022
BackgroundCytochrome P450 Family 1 Subfamily A Member 1 (CYP1A1) pathway, which is regulated by aryl hydrocarbon receptor (AhR) plays an important role in chemical carcinogenesis and xenobiotic metabolism.
Sweta Ghosh, Bhagavatula Moorthy, Bodduluri Haribabu, Venkatakrishna Rao Jala   +3 more
doaj   +1 more source

Characterization and expression analysis of Staphylococcus aureus pathogenicity island 3 - Implications for the evolution of staphylococcal pathogenicity islands [PDF]

, 2002
We describe the complete sequence of the 15.9-kb staphylococcal pathogenicity island 3 encoding staphylococcal enterotoxin serotypes B, K, and Q. The island, which meets the generally accepted definition of pathogenicity islands, contains 24 open reading
Kapur, Vivek, McCormick, John K., Orwin, Paul M., Paustian, Michael L., Schlievert, Patrick M., Yarwood, Jeremy M.   +5 more
core  

Fungal microbiota from rain water and pathogenicity of Fusarium species isolated from atmospheric dust and rainfall dust [PDF]

, 2011
In order to determine the presence of Fusarium spp. in atmospheric dust and rainfall dust, samples were collected during September 2007, and July, August, and October 2008.
A Bovallius, A Moreno, C. Iglesias, CM Messiaen, D Palmero, D Palmero, D. Palmero, DG Schmale, DW Griffin, DW Griffin, DW Griffin, DW Griffin, DW Griffin, F. Camacho, GL Schumann, H Komada, HL Barnett, HM Ho, J. C. Tello, J. M. Rodríguez, JC Tello, JF Leslie, JJ Ooka, JKM Brown, JL Díaz, JM Prospero, JM Prospero, JP Béthoux, M. de Cara, MA Ismail, ML Smither-Kopperl, PC Wu, PE Nelson, S Guerzoni, SII Abdel-Hafez, WGD Fernando, WH Elmer   +36 more
core   +2 more sources

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

The Equal Neutralizing Effectiveness of BNT162b2, ChAdOx1 nCoV-19, and Sputnik V Vaccines in the Palestinian Population

Vaccines
Since the beginning of the COVID-19 pandemic, different viral vector-based and mRNA vaccines directed against the SARS-CoV-2 “S” spike glycoprotein have been developed and have shown a good profile in terms of safety and efficacy.
Alexia Damour, Muriel Faure, Nicolas Landrein, Jessica Ragues, Narda Ardah, Haneen Dhaidel, Marie-Edith Lafon, Harald Wodrich, Walid Basha   +8 more
doaj   +1 more source