Results 111 to 120 of about 1,904,989 (338)
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Correction: The Irish potato famine pathogen Phytophthora infestans translocates the CRN8 kinase into host plant cells. [PDF]
PLoS Pathogens, 2015 PLOS Pathogens Staff
doaj +1 more source
PHI-base: a new interface and further additions for the multi-species pathogen–host interactions database [PDF]
, 2016 Martin Urban +10 more
openalex +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Correction: Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection. [PDF]
PLoS Pathogens, 2015 PLOS Pathogens Staff
doaj +1 more source
Sensors, 2009 The development of sensors for detecting foodborne pathogens has been motivated by the need to produce safe foods and to provide better healthcare. However, in the more recent times, these needs have been expanded to encompass issues relating to biosecurity, detection of plant and soil pathogens, microbial communities, and the environment. The range of
openaire +3 more sources
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Correction: IFNγ signaling endows DCs with the capacity to control type I inflammation during parasitic infection through promoting T-bet+ regulatory T cells. [PDF]
PLoS Pathogens, 2015 PLOS Pathogens Staff
doaj +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Host–pathogen evolutionary signatures reveal dynamics and future invasions of vampire bat rabies [PDF]
, 2016 Daniel G. Streicker +9 more
openalex +1 more source