Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Correction: XRN1 Is a Species-Specific Virus Restriction Factor in Yeasts. [PDF]
PLoS Pathogens, 2016 [This corrects the article DOI: 10.1371/journal.ppat.1005890.].
PLOS Pathogens Staff
doaj +1 more source
Mechanisms of Antimicrobial Resistance in ESKAPE Pathogens
BioMed Research International, 2016 The ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species) are the leading cause of nosocomial infections throughout the world.
Sirijan Santajit, N. Indrawattana
semanticscholar +1 more source
Studying pathogens degrades BLAST-based pathogen identification
Scientific Reports, 2022 AbstractAs synthetic biology becomes increasingly capable and accessible, it is likewise increasingly critical to be able to make accurate biosecurity determinations regarding the pathogenicity or toxicity of particular nucleic acid or amino acid sequences.
Jacob Beal, Adam Clore, Jeff Manthey
openaire +3 more sources
Yin and yang of interleukin-17 in host immunity to infection [version 1; referees: 2 approved] [PDF]
, 2017 The interleukin-17 (IL-17) family cytokines, such as IL-17A and IL-17F, play important protective roles in host immune response to a variety of infections such as bacterial, fungal, parasitic, and viral.
Das, Shibali, Khader, Shabaana
core +3 more sources
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Correction: Correction: AIG1 affects in vitro and in vivo virulence in clinical isolates of Entamoeba histolytica. [PDF]
PLoS Pathogens, 2018 [This corrects the article DOI: 10.1371/journal.ppat.1007091.].
PLOS Pathogens Staff
doaj +1 more source
Visacane, an innovative quarantine tool for the exchange of pest and disease-free sugarcane germplasm [PDF]
, 2011 Sugarcane varietal improvement can not exclusively rely upon exchange and introduction of genetic resources via true seeds (fuzz). It also requires the introduction of vegetative propagation material (cuttings, tissue-cultured plantlets).
Fernandez, Emmanuel +4 more
core
Effective elimination of Staphylococcal contamination from hospital surfaces by a bacteriophage-probiotic sanitation strategy: a monocentric study. [PDF]
, 2019 Persistent contamination of hospital surfaces and antimicrobial resistance (AMR) are recognized major causes of healthcare-associated infections (HAI). We recently showed that a probiotic-based sanitation (PCHS) can stably decrease surface pathogens and ...
BISI, Matteo +6 more
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source