Results 91 to 100 of about 4,237,903 (401)

Dual-channel Prototype Network for few-shot Classification of Pathological Images [PDF]

open access: yesarXiv, 2023
In pathology, the rarity of certain diseases and the complexity in annotating pathological images significantly hinder the creation of extensive, high-quality datasets. This limitation impedes the progress of deep learning-assisted diagnostic systems in pathology.
arxiv  

Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline

open access: yesNature, 2018
Cellular senescence, which is characterized by an irreversible cell-cycle arrest1 accompanied by a distinctive secretory phenotype2, can be induced through various intracellular and extracellular factors.
Tyler J. Bussian   +5 more
semanticscholar   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

Label‐free imaging of non‐deparaffinized sections of the human kidney to determine tissue quality and signatures of disease

open access: yesPhysiological Reports, 2022
Label‐free fluorescence imaging of kidney sections can provide important morphological information, but its utility has not been tested in a histology processing workflow.
Angela R. Sabo   +7 more
doaj   +1 more source

Semi-supervised Pathology Segmentation with Disentangled Representations [PDF]

open access: yesMICCAI-2020 DART workshop, 2020
Automated pathology segmentation remains a valuable diagnostic tool in clinical practice. However, collecting training data is challenging. Semi-supervised approaches by combining labelled and unlabelled data can offer a solution to data scarcity.
arxiv  

A Review on the Applications of Crowdsourcing in Human Pathology

open access: yes, 2017
The advent of the digital pathology has introduced new avenues of diagnostic medicine. Among them, crowdsourcing has attracted researchers' attention in the recent years, allowing them to engage thousands of untrained individuals in research and ...
Alialy, Roshanak   +6 more
core   +2 more sources

Observational Study Design in Veterinary Pathology, Part 1: Study Design [PDF]

open access: yes, 2018
Observational studies are the basis for much of our knowledge of veterinary pathology and are highly relevant to the daily practice of pathology. However, recommendations for conducting pathology-based observational studies are not readily available.
Amanda P. Beck   +22 more
core   +2 more sources

Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry

open access: yesActa Neuropathologica, 2006
Assessment of Alzheimer’s disease (AD)-related neurofibrillary pathology requires a procedure that permits a sufficient differentiation between initial, intermediate, and late stages.
H. Braak   +4 more
semanticscholar   +1 more source

Pathology of asthma [PDF]

open access: yesFrontiers in Microbiology, 2013
Asthma is a serious health and socioeconomic issue all over the world, affecting more than 300 million individuals. The disease is considered as an inflammatory disease in the airway, leading to airway hyperresponsiveness, obstruction, mucus hyper-production and airway wall remodeling.
Ichiro Aoki   +2 more
openaire   +4 more sources

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha   +6 more
wiley   +1 more source

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