Results 91 to 100 of about 2,215,729 (248)

Dual X-ray absorptiometry has limited utility in detecting bone pathology in children with hypophosphatasia: A pooled post hoc analysis of asfotase alfa clinical trial data

, 2020
Jill H. Simmons, Eric T. Rush, Anna Petryk, Shanggen Zhou, Gabriel Ángel Martos‐Moreno   +4 more
openalex   +2 more sources

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

Molecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa, Julia Richert, Tomasz Stokowy, Alicja Staśczak, Mariusz Szajewski, Maciej Ciesielski, Petra M. Grešner, Bartłomiej Tomasik, Łukasz Arcimowicz, Agnieszka Stankiewicz, Grażyna Suchodolska, Elżbieta Senkus, Wiesław Kruszewski, Anna J. Żaczek, Aleksandra Markiewicz   +14 more
wiley   +1 more source

Colorectal cancer pathology reporting: a regional audit [PDF]

, 1997

openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Routine Histopathological Evaluation of Benign Anorectal Interventions: Essentiality or Excess?

Gazi Medical Journal
Objective: To evaluate the necessity of routine histopathological examination in benign anorectal surgeries and to explore the potential for a selective approach based on patient characteristics. Methods: Retrospective analysis of patients who underwent
Ramazan Kozan, Enes Aksu, Kürşat Dikmen   +2 more
doaj   +1 more source

Disease Stage Characterization of Hepatorenal Fibrocystic Pathology in the PCK Rat Model of ARPKD [PDF]

, 2010
S. B. Mason, Yun Liang, Rachel M. Sinders, Caroline Miller, Tracy Eggleston‐Gulyas, Robin Crisler‐Roberts, Peter C. Harris, Vincent H. Gattone   +7 more
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Characterization of early-stage lesions and investigation on the role of mucosal trauma in hemorrhagic bowel syndrome in cattle

Veterinary Quarterly
Hemorrhagic bowel syndrome (HBS) is characterized by a dissecting intramucosal hematoma at the small bowel, causing obstruction and severe hemorrhage in dairy cattle.
Bert De Jonge, Bart Pardon, Jozefien Callens, Koen Chiers   +3 more
doaj   +1 more source

Biomodeling of pulmonary pathologies by means of intratracheal instillation of sensitizing substances in laboratory animals

, 2021
L. A. Taboyakova, О. В. Алимкина, N. S. Ogneva, Е. С. Савченко   +3 more
openalex   +2 more sources

TRPV1-Mediated Microglial Autophagy Attenuates Alzheimer’s Disease-Associated Pathology and Cognitive Decline [PDF]

, 2022
Chenfei Wang, Wei Huang, Jia Lu, Hongzhuan Chen, Zhihua Yu   +4 more
openalex   +1 more source