Results 11 to 20 of about 940,129 (290)
Metabolic Syndrome: Updates on Pathophysiology and Management in 2021
International Journal of Molecular Sciences, 2022 Metabolic syndrome (MetS) forms a cluster of metabolic dysregulations including insulin resistance, atherogenic dyslipidemia, central obesity, and hypertension.
Gracia Fahed +6 more
semanticscholar +1 more source
Oxidative Stress in Liver Pathophysiology and Disease
Antioxidants, 2023 The liver is an organ that is particularly exposed to reactive oxygen species (ROS), which not only arise during metabolic functions but also during the biotransformation of xenobiotics.
A. Allameh +4 more
semanticscholar +1 more source
Cognitive impairment in schizophrenia: aetiology, pathophysiology, and treatment
Molecular Psychiatry, 2023 Cognitive deficits are a core feature of schizophrenia, account for much of the impaired functioning associated with the disorder and are not responsive to existing treatments.
R. McCutcheon, R. Keefe, P. McGuire
semanticscholar +1 more source
COVID-19 pathophysiology: A review
Clinical Immunology, 2020 In December 2019, a novel coronavirus, now named as SARS-CoV-2, caused a series of acute atypical respiratory diseases in Wuhan, Hubei Province, China. The disease caused by this virus was termed COVID-19.
Koichi Yuki +2 more
semanticscholar +1 more source
Pathophysiology, 2022 The anterior cruciate ligament (ACL) is a commonly injured ligament in the knee. Bone tunnel widening is a known phenomenon after soft-tissue ACL reconstruction and etiology and the clinical relevance has not been fully elucidated.
Ruth Solomon +2 more
doaj +1 more source
Pathophysiology of Inflammatory Bowel Disease: Innate Immune System
International Journal of Molecular Sciences, 2023 Inflammatory bowel disease (IBD), comprising Crohn’s disease (CD) and ulcerative colitis (UC), is a heterogeneous state of chronic intestinal inflammation with no exact known cause.
Angela Sáez +4 more
semanticscholar +1 more source
Pathophysiology, 2022 Low-intensity systemic inflammation is an important element of heart failure pathogenesis. The aim of this study is to assess proinflammatory status serum indicators (C-reactive protein (CRP), tumor necrosis factor alpha (TNF-α), interleukin-6 (IL-6)) in
Anton V. Barsukov +4 more
doaj +1 more source
Pathophysiology of Type 2 Diabetes Mellitus
International Journal of Molecular Sciences, 2020 Type 2 Diabetes Mellitus (T2DM), one of the most common metabolic disorders, is caused by a combination of two primary factors: defective insulin secretion by pancreatic β-cells and the inability of insulin-sensitive tissues to respond appropriately to ...
U. Galicia-Garcia +7 more
semanticscholar +1 more source
Pathophysiology of obesity and its associated diseases
Acta Pharmaceutica Sinica B, 2023 The occurrence of obesity has increased across the whole world. Many epidemiological studies have indicated that obesity strongly contributes to the development of cancer, cardiovascular diseases, type 2 diabetes, liver diseases and other disorders ...
Xin Jin +7 more
semanticscholar +1 more source
Pathophysiology, 2022 Pain and nociception are different phenomena. Nociception is the result of complex activity in sensory pathways. On the other hand, pain is the effect of interactions between nociceptive processes, and cognition, emotions, as well as the social context ...
Marco Cascella +6 more
doaj +1 more source