Results 41 to 50 of about 1,115,813 (356)

Definition, Epidemiology, Pathophysiology, and Essential Criteria for Diagnosis of Pediatric Chronic Myeloid Leukemia

, 2021
Depending on the analytical tool applied, the hallmarks of chronic myeloid leukemia (CML) are the Philadelphia Chromosome and the resulting mRNA fusion transcript BCR-ABL1.
Markus Metzler, Meinolf Suttorp, Stephanie Sembill, Metzler, Markus, Frédéric Millot, Deutsch, Hélène, Suttorp, Meinolf, Sembill, Stephanie, Hélène Deutsch, Millot, Frédéric   +9 more
core   +1 more source

Treatment Strategies for Chronic Coronary Heart Disease with Left Ventricular Systolic Dysfunction or Preserved Ejection Fraction—A Systematic Review and Meta-Analysis

Pathophysiology, 2023
In this meta-analysis, we examine the advantages of invasive strategies for patients diagnosed with chronic coronary heart disease (CHD) and preserved left ventricular (LV) function, as well as those with significant LV systolic dysfunction (LV ejection ...
Elena Zelikovna Golukhova, Inessa Viktorovna Slivneva, Olga Sergeevna Kozlova, Bektur Shukurbekovich Berdibekov, Ivan Ivanovich Skopin, Vadim Yuryevich Merzlyakov, Renat Kamilyevich Baichurin, Igor Yuryevich Sigaev, Milena Abrekovna Keren, Mikhail Durmishkhanovich Alshibaya, Damir Ildarovich Marapov, Milena Artemovna Arzumanyan   +11 more
doaj   +1 more source

The Pathophysiology and Treatment of Glaucoma

Journal of the American Medical Association (JAMA), 2014
IMPORTANCE Glaucoma is a worldwide leading cause of irreversible vision loss. Because it may be asymptomatic until a relatively late stage, diagnosis is frequently delayed.
R. Weinreb, T. Aung, F. Medeiros
semanticscholar   +1 more source

CKD Urine Metabolomics: Modern Concepts and Approaches

Pathophysiology, 2023
One of the primary challenges regarding chronic kidney disease (CKD) diagnosis is the absence of reliable methods to detect early-stage kidney damage.
Elena Y. Danilova, Anna O. Maslova, Andrey N. Stavrianidi, Alexander E. Nosyrev, Larisa D. Maltseva, Olga L. Morozova   +5 more
doaj   +1 more source

Pathophysiology of Asthma [PDF]

British Journal of Clinical Pharmacology, 1996
1Our understanding of asthma and its therapy has changed markedly over the last few years, particularly with the application of molecular and cell biology and the discovery of new and more specific pharmacological tools. 2Many inflammatory cells participate in the inflammatory process in asthma and mediate a complex mixture of mediators. Cytokines are
openaire   +2 more sources

Lifestyle, Oxidative Stress, and Antioxidants: Back and Forth in the Pathophysiology of Chronic Diseases

Frontiers in Physiology, 2020
Oxidative stress plays an essential role in the pathogenesis of chronic diseases such as cardiovascular diseases, diabetes, neurodegenerative diseases, and cancer. Long term exposure to increased levels of pro-oxidant factors can cause structural defects
M. Sharifi-Rad, N. V. Anil Kumar, P. Zucca, E. Varoni, L. Dini, E. Panzarini, J. Rajković, P. T. Tsouh Fokou, E. Azzini, I. Peluso, Abhay Prakash Mishra, M. Nigam, Youssef El Rayess, M. Beyrouthy, L. Polito, M. Iriti, N. Martins, M. Martorell, A. Docea, W. Setzer, D. Calina, W. Cho, Javad Sharifi‐Rad   +22 more
semanticscholar   +1 more source

Update on the pathophysiology of cluster headache: Imaging and neuropeptide studies [PDF]

, 2022
Objective Cluster headache (CH) is the most severe primary headache condition. Its pathophysiology is multifaceted and incompletely understood. This review brings together the latest neuroimaging and neuropeptide evidence on the pathophysiology of CH ...
Ahmed, F., Boland, J. W., Buture, A., Dikomitis, L.   +3 more
core   +1 more source

sPAP/PAAT Ratio as a New Index of Pulmonary Vascular Load: A Study in Normal Subjects and Ssc Patients with and without PH

Pathophysiology, 2022
In pulmonary hypertension (PH), the development of right ventricular (RV) dilatation and RV failure are signs of accelerated progression of the disease, resulting in an increased risk of cardiac death.
Walter Serra, Alfredo Chetta
doaj   +1 more source

Conservative Management of Spontaneous Left Main Coronary Artery Dissection (SCAD) Triggered by Emotional Stress in the Late Postpartum Period: Case Report and Pathophysiology

Pathophysiology, 2022
A spontaneous coronary artery dissection (SCAD) during the postpartum period is a serious medical emergency and the most important non-atherosclerotic cause of coronary artery disease (CAD) in this population. While conservative management is recommended
Jaksa Zanchi, Dino Miric, Lovel Giunio, Anteo Bradaric Slujo, Mislav Lozo, Duje Erceg, Duje Orsulic, Josip A. Borovac   +7 more
doaj   +1 more source

Pathophysiology of Migraine

Annual Review of Physiology, 2013
Migraine is a collection of perplexing neurological conditions in which the brain and its associated tissues have been implicated as major players during an attack. Once considered exclusively a disorder of blood vessels, compelling evidence has led to the realization that migraine represents a highly choreographed interaction between major inputs from
PIETROBON, DANIELA, Moskowitz MA
openaire   +4 more sources