Results 31 to 40 of about 1,115,813 (356)

COVID-19 pathophysiology: A review

open access: yesClinical Immunology, 2020
In December 2019, a novel coronavirus, now named as SARS-CoV-2, caused a series of acute atypical respiratory diseases in Wuhan, Hubei Province, China. The disease caused by this virus was termed COVID-19.
Koichi Yuki   +2 more
semanticscholar   +1 more source

Urinary Transthyretin as a Biomarker in ATTRv Val50Met Amyloidosis

open access: yesPathophysiology, 2022
Transthyretin (TTR), the precursor protein for amyloidogenic TTR (ATTR) amyloidosis, forms tetramers and escapes glomerular filtration by binding with thyroxine and retinol-binding protein.
Hiroaki Matsushita   +6 more
doaj   +1 more source

Pathophysiology of Inflammatory Bowel Disease: Innate Immune System

open access: yesInternational Journal of Molecular Sciences, 2023
Inflammatory bowel disease (IBD), comprising Crohn’s disease (CD) and ulcerative colitis (UC), is a heterogeneous state of chronic intestinal inflammation with no exact known cause.
Angela Sáez   +4 more
semanticscholar   +1 more source

High Sucrose and Cholic Acid Diet Triggers PCOS-like Phenotype and Reduces Enterobacteriaceae Colonies in Female Wistar Rats

open access: yesPathophysiology, 2022
Polycystic ovary syndrome (PCOS), a common hormonal disorder in women of reproductive age, is associated with a poor and unhealthy diet. This study aimed to investigate the effect of a high sucrose and cholic acid (HSCA) diet in the presence of PCOS-like
I Made Putra Juliawan   +4 more
doaj   +1 more source

Pathophysiology of obesity and its associated diseases

open access: yesActa Pharmaceutica Sinica B, 2023
The occurrence of obesity has increased across the whole world. Many epidemiological studies have indicated that obesity strongly contributes to the development of cancer, cardiovascular diseases, type 2 diabetes, liver diseases and other disorders ...
Xin Jin   +7 more
semanticscholar   +1 more source

Chronic Fatigue Exhibits Heterogeneous Autoimmunity Characteristics Which Reflect Etiology

open access: yesPathophysiology, 2022
Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is considered to be associated with post-viral complications and mental stress, but the role of autoimmunity also remains promising.
Olga V. Danilenko   +2 more
doaj   +1 more source

Role of gut microbiota in type 2 diabetes pathophysiology

open access: yesEBioMedicine, 2020
A substantial body of literature has provided evidence for the role of gut microbiota in metabolic diseases including type 2 diabetes. However, reports vary regarding the association of particular taxonomic groups with disease. In this systematic review,
M. Gurung   +6 more
semanticscholar   +1 more source

Takotsubo Syndrome: Pathophysiology, Emerging Concepts and Clinical Implications

open access: yesCirculation, 2022
Takotsubo syndrome is a condition characterized by acute transient left ventricular systolic dysfunction, which at presentation can be challenging to distinguish from acute myocardial infarction.
T. Singh   +5 more
semanticscholar   +1 more source

Tuberculosis and Autoimmunity

open access: yesPathophysiology, 2022
Tuberculosis remains a common and dangerous chronic bacterial infection worldwide. It is long-established that pathogenesis of many autoimmune diseases is mainly promoted by inadequate immune responses to bacterial agents, among them Mycobacterium ...
Irina V. Belyaeva   +2 more
doaj   +1 more source

Pathophysiology and mechanism of long COVID: a comprehensive review

open access: yesAnnals medicus, 2022
Background After almost 2 years of fighting against SARS-CoV-2 pandemic, the number of patients enduring persistent symptoms long after acute infection is a matter of concern.
D. Castanares-Zapatero   +8 more
semanticscholar   +1 more source

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