Results 11 to 20 of about 636,522 (267)

Adhesion Molecules ICAM-1 and PECAM-1 as Potential Biomarkers of Central Nervous System Damage in Women Breast Cancer Survivors

open access: yesPathophysiology, 2022
Breast cancer (BC) is the most common tumor in women worldwide with high mortality rates. Surgical methods followed by radio–chemotherapy are used to treat these tumors.
Maria Pospelova   +15 more
doaj   +1 more source

Polymorphism in Adiponectin and Adiponectin Receptor Genes in Diabetes Mellitus Pathogenesis

open access: yesPathophysiology, 2022
The role played by hereditary factors in the development of diabetes mellitus type 2 (DM2) has not yet been fully established. Therefore, the purpose of our study was to investigate the prevalence of adiponectin and polymorphism in its gene receptors in ...
Iuliana Shramko   +9 more
doaj   +1 more source

New Clinical Phenotype of the Post-Covid Syndrome: Fibromyalgia and Joint Hypermobility Condition

open access: yesPathophysiology, 2022
Fibromyalgia can be defined as a chronic pain condition, affecting the musculoskeletal system, etiology and pathophysiology of which is sufficiently understudied.
Natalia Gavrilova   +6 more
doaj   +1 more source

Impact of Prematurity on Auditory Processing in Children

open access: yesPathophysiology, 2023
Prematurity is one of the most crucial risk factors negatively affecting the maturation of the auditory system. Children born preterm demonstrate high rates of hearing impairments. Auditory processing difficulties in preterm children might be a result of
Maria Y. Boboshko   +4 more
doaj   +1 more source

Combination Therapy with Enalapril and Paricalcitol Ameliorates Streptozotocin Diabetes-Induced Testicular Dysfunction in Rats via Mitigation of Inflammation, Apoptosis, and Oxidative Stress

open access: yesPathophysiology, 2023
Background: As the impacts of diabetes-induced reproductive damage are now evident in young people, we are now in urgent need to devise new ways to protect and enhance the reproductive health of diabetic people.
Magdy Y. Elsaeed   +17 more
doaj   +1 more source

Pathophysiology of Childhood-Onset Myasthenia: Abnormalities of Neuromuscular Junction and Autoimmunity and Its Background

open access: yesPathophysiology, 2023
The pathophysiology of myasthenia gravis (MG) has been largely elucidated over the past half century, and treatment methods have advanced. However, the number of cases of childhood-onset MG is smaller than that of adult MG, and the treatment of childhood-
Masatoshi Hayashi
doaj   +1 more source

Pathophysiology of Asthma [PDF]

open access: yesBritish Journal of Clinical Pharmacology, 1996
1Our understanding of asthma and its therapy has changed markedly over the last few years, particularly with the application of molecular and cell biology and the discovery of new and more specific pharmacological tools. 2Many inflammatory cells participate in the inflammatory process in asthma and mediate a complex mixture of mediators. Cytokines are
openaire   +2 more sources

The Emerging Role of Heat Shock Factor 1 (HSF1) and Heat Shock Proteins (HSPs) in Ferroptosis

open access: yesPathophysiology, 2023
Cells employ a well-preserved physiological stress response mechanism, termed the heat shock response, to activate a certain type of molecular chaperone called heat shock proteins (HSPs).
Iman Aolymat   +2 more
doaj   +1 more source

Unraveling MYC’s Role in Orchestrating Tumor Intrinsic and Tumor Microenvironment Interactions Driving Tumorigenesis and Drug Resistance

open access: yesPathophysiology, 2023
The transcription factor MYC plays a pivotal role in regulating various cellular processes and has been implicated in tumorigenesis across multiple cancer types.
Zinab O. Doha, Rosalie C. Sears
doaj   +1 more source

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