Results 21 to 30 of about 1,115,813 (356)
Pathophysiology, 2020 The aim of this research was to correlate indicators of proinflammatory status and the structural/functional characteristics of the cardiovascular system comparatively in male and female patients with essential hypertension (EH) complicated by diastolic ...
Anton V. Barsukov +6 more
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Role of dopamine in the pathophysiology of Parkinson’s disease
Translational Neurodegeneration, 2023 A pathological feature of Parkinson’s disease (PD) is the progressive loss of dopaminergic neurons and decreased dopamine (DA) content in the substantia nigra pars compacta in PD brains. DA is the neurotransmitter of dopaminergic neurons.
Z. Zhou +4 more
semanticscholar +1 more source
Pathophysiology, 2022 The increased glycation of elastin is an important factor in vascular changes in diabetes. Using the ELISA method, we determined serum levels of IgM and IgG autoantibodies to advanced glycation end products of vascular elastin (anti-AGE EL IgM and anti ...
Krasimir Kostov, Alexander Blazhev
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Pathophysiology, 2020 The goal of our study was to analyze the time course of the effect of NG-nitro-L-arginine methyl ester (L-NAME) on nitric oxide synthase (NOS) isoforms and nuclear factor–κB (NF-κB) protein expression, total NOS activity, and blood pressure (BP) in rats.
Olga Pechanova +2 more
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Pathophysiology, 2022 Intravesical chemotherapy may cause chemical cystitis and related lower urinary tract symptoms (LUTS). The aims of this study were to evaluate the efficacy and safety of an oral preparation of hyaluronic acid (HA), chondroitin sulfate (CS), curcumin, and
Celeste Manfredi +17 more
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Pathophysiology, 2022 The anterior cruciate ligament (ACL) is a commonly injured ligament in the knee. Bone tunnel widening is a known phenomenon after soft-tissue ACL reconstruction and etiology and the clinical relevance has not been fully elucidated.
Ruth Solomon +2 more
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Pathophysiology of Type 2 Diabetes Mellitus
International Journal of Molecular Sciences, 2020 Type 2 Diabetes Mellitus (T2DM), one of the most common metabolic disorders, is caused by a combination of two primary factors: defective insulin secretion by pancreatic β-cells and the inability of insulin-sensitive tissues to respond appropriately to ...
U. Galicia-Garcia +7 more
semanticscholar +1 more source
Pathophysiology, 2022 Low-intensity systemic inflammation is an important element of heart failure pathogenesis. The aim of this study is to assess proinflammatory status serum indicators (C-reactive protein (CRP), tumor necrosis factor alpha (TNF-α), interleukin-6 (IL-6)) in
Anton V. Barsukov +4 more
doaj +1 more source
Cognitive impairment in schizophrenia: aetiology, pathophysiology, and treatment
Molecular Psychiatry, 2023 Cognitive deficits are a core feature of schizophrenia, account for much of the impaired functioning associated with the disorder and are not responsive to existing treatments.
R. McCutcheon, R. Keefe, P. McGuire
semanticscholar +1 more source
Pathophysiology, 2022 Pain and nociception are different phenomena. Nociception is the result of complex activity in sensory pathways. On the other hand, pain is the effect of interactions between nociceptive processes, and cognition, emotions, as well as the social context ...
Marco Cascella +6 more
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