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In this meta-analysis, we examine the advantages of invasive strategies for patients diagnosed with chronic coronary heart disease (CHD) and preserved left ventricular (LV) function, as well as those with significant LV systolic dysfunction (LV ejection ...
Elena Zelikovna Golukhova +11 more
doaj +1 more source
CKD Urine Metabolomics: Modern Concepts and Approaches
One of the primary challenges regarding chronic kidney disease (CKD) diagnosis is the absence of reliable methods to detect early-stage kidney damage.
Elena Y. Danilova +5 more
doaj +1 more source
Pancreatic cancer cachexia: a review of mechanisms and therapeutics. [PDF]
Over the last decade, we have gained new insight into the pathophysiology of cachexia associated with pancreatic cancer. Unfortunately, its treatment is complex and remains a challenge.
Andrew Eugene Hendifar +8 more
core +2 more sources
In pulmonary hypertension (PH), the development of right ventricular (RV) dilatation and RV failure are signs of accelerated progression of the disease, resulting in an increased risk of cardiac death.
Walter Serra, Alfredo Chetta
doaj +1 more source
Diabetes mellitus and ischemic heart disease. the role of ion channels [PDF]
Diabetes mellitus is one the strongest risk factors for cardiovascular disease and, in particular, for ischemic heart disease (IHD). The pathophysiology of myocardial ischemia in diabetic patients is complex and not fully understood: some diabetic ...
De Marchis, Marialaura +8 more
core +2 more sources
A spontaneous coronary artery dissection (SCAD) during the postpartum period is a serious medical emergency and the most important non-atherosclerotic cause of coronary artery disease (CAD) in this population. While conservative management is recommended
Jaksa Zanchi +7 more
doaj +1 more source
Stable coronary syndromes: pathophysiology, diagnostic advances and therapeutic need [PDF]
The diagnostic management of patients with angina pectoris typically centres on the detection of obstructive epicardial CAD, which aligns with evidence-based treatment options that include medical therapy and myocardial revascularisation.
Berry, Colin +2 more
core +1 more source
The Endothelial Glycocalyx and Retinal Hemodynamics
Purpose. Previous studies suggest that the endothelial glycocalyx adds to vascular resistance, inhibits thrombosis, and is critical for regulating homogeneous blood flow and ensuring uniform red blood cell (RBC) distribution. However, these functions and
Gaganpreet Kaur +2 more
doaj +1 more source
Serotonin and motherhood: From molecules to mood [PDF]
Emerging research points to a valuable role of the monoamine neurotransmitter, serotonin, in the display of maternal behaviors and reproduction-associated plasticity in the maternal brain.
Li, Ming +2 more
core +3 more sources
Transforming growth factor beta (TGFβ) is a versatile cytokine. Although a profibrotic role of TGFβ is well established, its effect on tissue inhibitor of metalloproteinase (TIMPs) and inflammatory mediators are incompletely described.
Babu Raja Maharjan +3 more
doaj +1 more source

